Results 201 to 210 of about 523,414 (266)

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Assessing the accuracy of the recording and reporting of malaria rapid diagnostic test results in four African countries: methods and key results. [PDF]

Malar J
Lindblade KA, Mpimbaza A, Ngufor C, Yavo W, Atobatele S, Akpiroroh E, Konaté-Touré A, Ahogni I, Ssewante N, Agaba B, Kpemasse A, Agnon J, Okoro O, Ntadom G, Tanoh A, Affoukou C, Opigo J, Cooper S, Aponte JJ, Griffith K, Soebiyanto R, Humes M.   +21 more
europepmc   +1 more source

Anti‐CD20 Discontinuation Versus Continuation in People Aged Over 50 With Non‐Active Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Alexia Moukhine, Fabien Rollot, Romain Casey, Nicolas Collongues, Sandra Vukusic, Guillaume Mathey, Anne Laure Dubessy, Jonathan Ciron, Jérôme De Seze, Aurélie Ruet, Pierre Labauge, Arnaud Kwiatkowski, Hélène Zephir, Caroline Papeix, Gilles Defer, Christine Lebrun‐Frenay, David Axel Laplaud, Eric Berger, Eric Thouvenot, Jean Pelletier, Abdullatif Al Khedr, Olivier Casez, Bertrand Bourre, Abir Wahab, Laurent Magy, Jean‐Philippe Camdessanché, Ines Doghri, Solène Moulin, Mariana Sarov Rivière, Karolina Hankiewicz, Amélie Dos Santos, Corinne Pottier, Eric Manchon, Jennifer Aboab, Maia Tchikviladze, Thomas David, Gilles Edan, Emmanuelle Le Page, Laure Michel, Anne Kerbrat, OFSEP Investigators   +40 more
wiley   +1 more source

A reason to celebrate in a time of uncertainty. Response to: Linblade et al. "Assessing the accuracy of the recording and reporting of malaria rapid diagnostic test results in four African countries-methods and key results". [PDF]

Malar J
Barat LM.
europepmc   +1 more source

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin, Sofia Waldorf, Janina von der Gablentz, Torsten Grehl, Huelya Nazlican, Thomas Meyer, Julian Grosskreutz, Patrick Weydt, Sarah Bernsen   +8 more
wiley   +1 more source

Clinical evaluation of a novel Mologic malaria Plasmodium falciparum LDH-dependent lateral flow rapid diagnostic test diagnostic accuracy: a cross-sectional study, Sudan. [PDF]

Malar J
Mohamed AO, Hamid MMA, Jebreel WMA, Elaagip A, Mohammed FO, Albsheer MM, Mustafa SA, Ahmed TME, Ahmed SBA, Chamai M, Dittrich S.   +10 more
europepmc   +1 more source

Assessment of a rapid diagnostic test based on loop-mediated isothermal amplification (LAMP) to identify the most frequent pathogens causing hospital-acquired pneumonia. [PDF]

Front Cell Infect Microbiol
Sellarès-Crous A, Martínez-Trejo A, Arnalda-Muñoz N, Gatti G, Villanueva-López M, Vergara-Gómez A, Marco-Reverté F, Espasa-Soley M, Vila-Estapé J.   +8 more
europepmc   +1 more source

Assessing the influence of rapid diagnostic test (RDT) accuracy on malaria misdiagnosis and antimalarial resistance in Nigeria. [PDF]

Ann Med Surg (Lond)
Okereke PU, Ayodeji BM, Bolarinwa RT, Ayodeji OD, Popoola IO, Okereke WO, Ogamba N, Nworah LU, Umeh CV, Okpechukwu CP, Ibekwe SN, Emeka E, Tola OS.   +12 more
europepmc   +1 more source

Correction: Performance evaluation of a combination Plasmodium dual-antigen CRP rapid diagnostic test in Lambaréné, Gabon. [PDF]

Infection
Alabi A, Musangomunei FP, Lotola-Mougeni F, Bie-Ondo JC, Murphy K, Essone PN, Kabwende AL, Mahmoudou S, Macé A, Harris V, Ramharter M, Grobusch MP, Yazdanbakhsh M, Fernandez-Carballo BL, Escadafal C, Kremsner PG, Dittrich S, Agnandji ST.   +17 more
europepmc   +1 more source

Field evaluation of the Bioline Malaria Ag P.f/Pan rapid diagnostic test: causes of microscopy discordance and performance in Uganda. [PDF]

Malar J
Kabbale KD, Nsengimaana B, Semakuba FD, Kagurusi BA, Mwubaha C, Wiringilimaana I, Katairo T, Kiyaga S, Mbabazi M, Gonahasa S, Kamya MR, Tukwasibwe S, Nsobya SL, Asua V, Jjingo D, Agaba B, Maiteki-Sebuguzi C, Opigo J, Hilton K, Staedke SG, Dorsey G, Conrad MD, Greenhouse B, Ssewanyana I, Briggs J.   +24 more
europepmc   +1 more source