Results 141 to 150 of about 36,635 (234)

Successful rapid desensitization to multiple insulin preparations in an adult with type 1 diabetes: a case report and literature review. [PDF]

Front Endocrinol (Lausanne)
Chen Y, Zhu W, Chen G, Yao J.
europepmc   +1 more source

Effect of Interleukin‐6 Inhibitors on Rheumatoid Arthritis Pain: Overview of Evidence and Mechanistic Pathways

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
This review synthesizes current mechanistic and clinical evidence on IL‐6 inhibitors, particularly sarilumab and tocilizumab, concerning their effect on pain in RA. ABSTRACT Rheumatoid arthritis (RA) is an autoimmune systemic disease in which pain remains a major and often refractory symptom even after clinical remission of the disease.
Andrej Belančić, Seher Sener, Almir Fajkić, Ines Potočnjak, Mirjana Stanić Benić, Marijana Vučković, Yusuf Ziya Sener, Marija Rogoznica Pavlović, Antonio Markotić, Josipa Radić, Mislav Radić   +10 more
wiley   +1 more source

Auxiliary TARP Subunits Define AMPA Receptor Pharmacology and Function. [PDF]

J Xenobiot
Bdir S, Çapan İ, Hawash M, Servi S, Qneibi M.   +4 more
europepmc   +1 more source

Physiological Responses to Virtual Reality‐Based Stress Regulation and Relaxation Interventions: A Systematic Review

Stress and Health, Volume 42, Issue 2, April 2026.
ABSTRACT Physiological markers are increasingly used to monitor individuals undergoing Virtual Reality (VR) stress interventions. However, several challenges arise when employing these markers to assess the impact of VR stress interventions. This systematic review synthesises and critically discusses the literature on VR stress interventions across ...
Lisanne M. Robbemond, Matthijs L. Noordzij, Catheleine M. G. van Driel, Wim Veling   +3 more
wiley   +1 more source

Understanding Biologics in CRSwNP: Related Events and Insights. [PDF]

Curr Allergy Asthma Rep
Izquierdo-Domínguez A, Al-Salloom Z, Viñas M, Mullol J, Alobid I.   +4 more
europepmc   +1 more source

The Acetylcholine Esterase Inhibitor Donepezil Increases Dopamine Levels in the Nucleus Accumbens and Blocks the Alcohol Deprivation Effect in Rats

Addiction Biology, Volume 31, Issue 4, April 2026.
This study examined the effects of donepezil on mesolimbic dopamine signalling and alcohol‐related behaviours in male rats. Donepezil increases nucleus accumbens dopamine via muscarinic mechanisms and prevented further dopamine elevation after alcohol administration. Although it did not reduce regular alcohol intake, it abolished relapse‐like drinking.
Anna Loftén, Klara Danielsson, Louise Adermark, Bo Söderpalm, Mia Ericson   +4 more
wiley   +1 more source

Successful Management of Aspirin Intolerance After Ad Hoc PCI: A Case Report and a Developed Algorithm. [PDF]

Clin Case Rep
Mohammadi K, Yaribash S, Mehrpooya M.
europepmc   +1 more source

Decreased Severity of Oral Immunotherapy Induced Gastrointestinal Eosinophilic Reactions Following Revisions in Milk‐Treatment Protocol

Allergy, Volume 81, Issue 4, Page 1219-1227, April 2026.
A revised milk OIT protocol with lower daily allergen load and slower dose escalation reduced the severity and delayed onset of OIT‐induced gastrointestinal eosinophilic reactions (OITIGER). Elevated baseline absolute eosinophil count (AEC > 600/μL) was a consistent independent risk factor for OITIGER, while older age was protective.
Na'ama Epstein‐Rigbi, Matan Elkan, Yair Tzarfati, Michael B. Levy, Liat Nachshon, Yael Koren, Yitzhak Katz, Arnon Elizur, Michael R. Goldberg   +8 more
wiley   +1 more source

Clinical and Etiopathological Perspective of Vitamin B1 Hypersensitivity and an Example of a Desensitization Protocol. [PDF]

Life (Basel)
Lis K.
europepmc   +1 more source

Comorbid Chronic Rhinosinusitis and Asthma: Shared Risk Factors and Treatment Implications—An EAACI Task Force Report

Allergy, Volume 81, Issue 4, Page 1000-1023, April 2026.
ABSTRACT Chronic rhinosinusitis (CRS) and asthma are prevalent conditions that often coexist. These diseases share common inflammatory mechanisms, such as T‐helper cell 2 (T2)‐high inflammation, driven by interleukin (IL)‐4, IL‐5, and IL‐13 cytokines.
Sanna Toppila‐Salmi, Sietze Reitsma, Valérie Hox, Simon Gane, Philippe Gevaert, Juan Maza‐Solano, Alma Helevä, Ida Sulku, Kaisa Santala, Iiris Kangasniemi, Ludger Klimek, Adam Chaker, Aspasia Karavelia, Michael Rudenko, Oliver Pfaar, Laura Van Gerven, Shaari Ariana, Michele Schiappoli, Marie Lundberg, Jan Hagemann, Ibon Eguíluz‐Gracia, Andre Moreira   +21 more
wiley   +1 more source