Results 41 to 50 of about 3,798,437 (293)

Patterns of early life body mass index and childhood overweight and obesity status at eight years of age

BMC Pediatrics, 2018
Background Excess weight gain in infancy and childhood is associated with increased risk of subsequent obesity. Identifying patterns of infancy and childhood weight gain associated with subsequent obesity or overweight status could help identify children
Joseph M. Braun, Heidi J. Kalkwarf, George D. Papandonatos, Aimin Chen, Bruce P. Lanphear   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Templated grain growth in rapid sintered 3D-printed alumina ceramics

Open Ceramics, 2023
Textured microstructures in ceramics have gained interest due to their beneficial effect on structural and functional properties. For instance, morphologically textured grains in alumina-based ceramics can increase their damage tolerance.
Anna-Katharina Hofer, Andraž Kocjan, Raul Bermejo   +2 more
doaj   +1 more source

Rapid aneurysm growth after transarterial chemoembolization [PDF]

Journal of Vascular Surgery Cases, 2015
Chemotherapy has been anecdotally related to aneurysm growth, but no correlation has been noted to date for localized transarterial chemoembolization. We present the case of a 64-year-old man with clearly documented accelerated aortic and iliac artery aneurysm dilation after two rounds of transarterial chemoembolization for hepatocellular carcinoma ...
Kirsten, Dansey, Dansey, Kirsten, Wooster, Mathew, Powell, Alexis, Rodriguez, Eduardo, Zwiebel, Bruce, Shames, Murray   +6 more
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Odds of Developing Overweight or Obesity Increase with Height Decile in Tall Healthy Weight Kindergarteners: Longitudinal Results from the West Virginia Coronary Artery Risk Detection In Appalachian Communities (WV CARDIAC) Project

Journal of Pediatrics: Clinical Practice
Objective: Childhood obesity is a strong predictor of adult obesity and chronic health complications. Prevention initiatives are most successful when implemented before excess weight gain, but tools to screen healthy weight children for obesity risk are ...
Maria A. Serrat, PhD, Eloise Elliott, PhD, Lee A. Pyles, MD, Christa L. Lilly, PhD   +3 more
doaj   +1 more source

The anatomy of high growth firms in Scotland [PDF]

, 2010
There is a growing volume of scholarly evidence from various countries which points to high growth firms (HGFs) as a key force fuelling economic growth.
Brown, Ross, Mason, Colin
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Growing pains: exploring residents’ mental health in a rapidly growing municipality—a qualitative study

Frontiers in Public Health
BackgroundBelonging to a community provides opportunities for engagement, social connectedness, and participation, which are important for mental health.
Ann-Grete Dybvik Akre, Marie Dahlen Granrud   +1 more
doaj   +1 more source