Results 41 to 50 of about 17,853 (215)

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

A Closer Look at the Laboratory Impact of Utilizing ePlex Blood Culture Identification Panels: a Workflow Analysis Using Rapid Molecular Detection for Positive Blood Cultures

Microbiology Spectrum, 2022
Rapid identification of pathogens is critical in bloodstream infections. We evaluated the diagnostic performance of the GenMark Dx ePlex blood culture identification (BCID) panels and the adoption of the ePlex system into the clinical laboratory workflow.
Giannoula S. Tansarli, Kimberle C. Chapin   +1 more
doaj   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

Comparative evaluation of two MALDI-TOF MS systems for microbial identification: accuracy and workflow efficiency in a clinical microbiology laboratory

Microbiology Spectrum
This study aimed to compare the identification accuracy and workflow of the VITEK MS PRIME (VMP) and the MALDI Biotyper Sirius (BS) in a routine laboratory setting. A total of 927 isolates, representing 219 different species, were analyzed using both the
Jasmin Köffer, Jale Ören, Ulrike Betz, Janhendrik Timm, Meike Oftring, Nina Bauer, Maxime Ndolumingo, Lelia Abad, Ulrich Eigner   +8 more
doaj   +1 more source

DNA barcoding coupled with high resolution melting for rapid identification of Ardisia gigantifolia and its toxic adulterants

Biotechnology & Biotechnological Equipment, 2021
Ardisia gigantifolia is a medicinal plant; its herbal medicinal product has played important roles in the ways of life of people in China. However, commercial products of this herbal medicine are frequently adulterated with Rhododendron molle root and ...
Bo Zhao, Chao Xiong, Lan Wu, Li Xiang, Yuhua Shi, Wei Sun, Shilin Chen   +6 more
doaj   +1 more source

Rapid identification of proteins. [PDF]

Proceedings of the National Academy of Sciences, 1993
The amino acid composition, molecular weight, and isoelectric point of a protein can all be easily and economically determined by current electrophoretic techniques. A method which uses such easily obtained data to identify proteins is described. A computer program first corrects for systematic errors in amino acid quantitation and then searches the ...
openaire   +2 more sources

T2* Magnetic Resonance Imaging Uncovers Hemosiderin Burden in Pediatric Hemophilia: A Call for Sensitive Imaging Biomarkers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemophilic arthropathy remains the leading morbidity in hemophilia despite modern prophylaxis, and early joint damage may be missed by routine exams. This study explored T2* MRI as a noninvasive biomarker of hemosiderin deposition in pediatric hemophilia.
Jessica Garcia, Tarique Hussain, Jeanne Dillenbeck, Matthew Hammer, Annette von Drygalski, Guy Young, Ayesha Zia   +6 more
wiley   +1 more source

Development of Loop-Mediated Isothermal Amplification (LAMP) Methods for Rapid Identification of Nephrotoxic Amanita Species

Mycobiology
Mushroom poisoning remains the leading cause of foodborne morbidity and mortality in China. The mushrooms that cause acute kidney injury (AKI) belong to the species of Amanita genus section Roanokenses.
Mengmeng Lai, Pengping Duan, Zhengmi He, Ping Zhang, Zuohong Chen   +4 more
doaj   +1 more source

Rapid identification of human‐infecting viruses [PDF]

Transboundary and Emerging Diseases, 2019
Viruses have caused much mortality and morbidity to humans and pose a serious threat to global public health. The virome with the potential of human infection is still far from complete. Novel viruses have been discovered at an unprecedented pace as the rapid development of viral metagenomics.
Zheng Zhang, Zena Cai, Zhiying Tan, Congyu Lu, Taijiao Jiang, Gaihua Zhang, Yousong Peng   +6 more
openaire   +2 more sources

ASSIST: Refinement of a Benefits Navigator Intervention Among Low‐Income Pediatric Oncology Families

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Children with cancer living in poverty experience worse survival and quality of life. Interventions connecting low‐income families to benefits (e.g., Supplemental Nutrition Assistance Program [SNAP] improve health outcomes; yet nearly 50% of SNAP‐eligible pediatric oncology families are unenrolled.
Puja J. Umaretiya, Selena Murcia Mendez, Jennifer Kellett, Sarah Wright, Marisel Ponton, Robin T. Higashi, Rahela Aziz‐Bose, Colleen A. Kelly, Ayesha Zia, Joanne Wolfe, Sandi L. Pruitt, Kira Bona   +11 more
wiley   +1 more source