Results 81 to 90 of about 186,072 (301)

A Rapid Intensification Warning Index for Tropical Cyclones Based on the Analog Method

Geophysical Research Letters, 2023
Prediction of the rapid intensification (RI) of tropical cyclones (TCs) remains challenging. In this paper, by using information from the early period following TC formation, the rapid intensification warning index (RIWI) is developed based on the analog
Deyu Lu, Ruiqiang Ding, Quanjia Zhong, Jiangyu Mao, Qian Zou, Jianping Li   +5 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Dynamic Forcing Behind Hurricane Lidia’s Rapid Intensification

Abstract. This study examines Hurricane Lidia’s rapid intensification (RI) in the understudied northeastern Pacific, focusing on its interaction with an upper-level trough. Using IFS-ECMWF ensemble forecasts and ERA5 reanalysis, we analyze the large-scale dynamical mechanisms driving Lidia’s intensification.
Mauricio López-Reyes, María Luisa Martín-Pérez, Carlos Calvo-Sancho, Juan Jesús González-Alemán   +3 more
openaire   +1 more source

Determinants of DMC technologies adoption among smallholders in the Lake Alaotra area, Madagascar : Document de travail BV lac n° 45 [PDF]

, 2008
Les techniques de systèmes de semis direct sur couverture végétale (SCV) sont diffusées depuis une dizaine d'années à Madagascar. Ils répondent à des objectifs de préservation de l'environnement, de création de revenus et de réduction de la pauvreté, en ...
Andriamalala, Herizo, Chabierski, Stéphane, Dabat, Marie-Hélène, Domas, Raphaël, Husson, Olivier, Penot, Eric   +5 more
core  

Evolution of small reservoirs in Burkina Faso [PDF]

, 2020
Small reservoirs (SRs) are important infrastructures for providing water for a wide range of activities in Burkina Faso and other semiarid environments.
Barron, Jennie, Cofie, Olufunke, Forkuor, Gerald   +2 more
core  

Rice Intensification in a Changing Environment: Impact on Water Availability in Inland Valley Landscapes in Benin [PDF]

, 2019
This study assesses the impact of climate change on hydrological processes under rice intensification in three headwater inland valley watersheds characterized by different land conditions.
Danvi, A., Diekkrüger, B., Giertz, S., Zwart, Sander J.   +3 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Camelids and sustainable development [PDF]

, 2015
Face to the global changes and new climatic constraints, the camel farming is confronted to new challenges, first to contribute to the “livestock revolution” (for reaching the requirements of a growing human population), especially in remote places of ...
Faye, Bernard
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Incorporating Hourly Convective Cloud Data Into Tropical Cyclone Rapid Intensification Forecasting With Machine Learning

Journal of Geophysical Research: Machine Learning and Computation
In this study, we developed a machine learning (ML) model to predict the rapid intensification (RI) of North Atlantic tropical cyclones (TCs) using 6‐hourly Statistical Hurricane Intensity Prediction Scheme (SHIPS) predictors and additional data on very ...
Qiaoyan Wu, Tong Luo, Jiacheng Hong
doaj   +1 more source