Results 61 to 70 of about 31,825 (254)

Characteristics of the convective bursts and their relationship with the rapid intensification of Super Typhoon Maria (2018)

Atmospheric and Oceanic Science Letters, 2020
For Super Typhoon Maria (2018), the multi-intensity change stages are identified and reproduced by numerical simulation. It is rather difficult to perform a perfect simulation for such a repeatedly reinforced typhoon during its long life-cycle and remote
Jian HENG, Shuai YANG, Yuanfa GONG, Jianfeng GU, Haiwen LIU   +4 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Transition Path Theory Insights into Hurricane Rapid Intensification

Abstract We examine hurricane and ocean reanalysis data to understand how rapid intensification (RI) of tropical cyclones is influenced by the upper ocean density structure, focusing on barrier layer (BL) thickness and thermocline depth in the eastern Caribbean Sea and the nearby western tropical North Atlantic.
Beron-Vera, F. J., Bonner, G., Olascoaga, M. J., Dong, S., Lopez, H.   +4 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Maximizing Simulated Tropical Cyclone Intensity With Action Minimization

Journal of Advances in Modeling Earth Systems, 2019
Direct computer simulation of intense tropical cyclones (TCs) in weather models is limited by computational expense. Intense TCs are rare and have small‐scale structures, making it difficult to produce large ensembles of storms at high resolution ...
David A. Plotkin, Robert J. Webber, Morgan E O'Neill, Jonathan Weare, Dorian S. Abbot   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Response of Tropical Cyclone Formation and Intensification Rates to Climate Warming in Idealized Simulations

Journal of Advances in Modeling Earth Systems, 2020
There is currently no theory for the rate of tropical cyclone (TC) formation given a particular climate, so our understanding of the relationship between TC frequency and large‐scale environmental factors is largely empirical.
Hamish A. Ramsay, Martin S. Singh, Daniel R. Chavas   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Convection, latent heating and potential temperature budget in the rapidly intensifying Typhoon Mujigae (2015)

Atmospheric Science Letters, 2019
Based on a 72‐hr simulation of the rapidly intensifying Typhoon Mujigae (2015), the spatiotemporal evolutions of various inner‐core convections and the associated latent heating (LH) features were investigated.
Xiba Tang, Shuai Yang, Fan Ping, Mengxia Li, Jing Peng   +4 more
doaj   +1 more source