Results 51 to 60 of about 31,825 (254)

Influence of global warming on the rapid intensification of western North Pacific tropical cyclones

open access: yesEnvironmental Research Letters, 2019
The rapid intensification (RI) of tropical cyclones (TCs) associated with global warming is a matter of concern worldwide. This study examines how the RI across the western North Pacific is related to the so-called ‘efficiency of intensity’ (EINT ...
Nam-Young Kang, James B Elsner
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Sharp Increase in rapid intensification of Arabian Sea tropical cyclones over the past decade

open access: yesCommunications Earth & Environment
The Arabian Sea has experienced a sharp increase in extremely severe tropical cyclones over the past decade, yet the drivers behind this trend remain unclear.
Xiaojing Li, Yi Li, Youmin Tang
doaj   +1 more source

Upper-tropospheric potential vorticity anomaly before the rapid intensification of Typhoon Mujigae (2015) and its response to reduced SST

open access: yesAtmospheric and Oceanic Science Letters, 2020
As the strongest typhoon in 2015, the rapid intensification (RI) process of Typhoon Mujigae is simulated at the cloud-resolving scale by utilizing the Weather Research and Forecasting model, coupled with observed sea surface temperature (SST) and reduced
Xiba TANG   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Increasing trend in rapid intensification magnitude of tropical cyclones over the western North Pacific

open access: yesEnvironmental Research Letters, 2020
Rapid intensification (RI) refers to a significant increase in tropical cyclone (TC) intensity over a short period of time. A TC can also undergo multiple RI events during its lifetime, and these RI events pose a significant challenge for operational ...
Jinjie Song   +2 more
doaj   +1 more source

Interdecadal Changes of Characteristics of Tropical Cyclone Rapid Intensification Over Western North Pacific

open access: yesIEEE Access, 2020
This study investigates the interdecadal variations of rapid intensification (RI) of tropical cyclones (TCs) over Western North Pacific (WNP) during 1960-2016, TC variabilities associated with RI and the possible mechanisms for such variations are also ...
Da Zhang   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

On the Realism of Tropical Cyclone Intensification in Global Storm‐Resolving Climate Models

open access: yesGeophysical Research Letters
The physical processes governing a tropical cyclone's lifecycle are largely understood, but key processes occur at scales below those resolved by global climate models. Increased resolution may help simulate realistic tropical cyclone intensification. We
Alexander J. Baker   +2 more
doaj   +1 more source

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