Results 111 to 120 of about 1,834,579 (310)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Informing NHS policy in ‘digital-first primary care’: a rapid evidence synthesis
Health Services and Delivery Research, 2019 Background: In ‘digital-first primary care’ models of health-care delivery, a patient’s first point of contact with a general practitioner or other health professional is through a digital channel, rather than a face-to-face consultation.
Mark Rodgers +4 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The effectiveness of structured physical activity on agitation in people with dementia: a rapid review [PDF]
Objectives: Managing agitation and other behaviours that challenge is a significant dementia care challenge. The priority is to find effective non-pharmacological interventions as drug treatments can have significant side effects.
Hoe, J. +3 more
core +1 more source
To what extent do lower-level offenders go on to commit more serious crimes? A rapid review [PDF]
, 2023 The aim of the project was to conduct a rapid review of the literature and develop a report summarising the evidence on perpetrators and/or offenders of violence against women and girls (VAWG) and whether committing lower-level offences leads to ...
Clark, Sigrún +2 more
core
Environmental surveillance of pathogens in Africa
Applied and Environmental MicrobiologyThe control of infectious diseases depends on effective diagnostics and interventions. In Africa, resource limitations hinder clinical surveillance.
Eric Darko +11 more
doaj +1 more source
مجله اپیدمیولوژی ایران, 2021 Background and Objectives: In the late 2019, the SARS-CoV-2 virus was identified as the cause of an outbreak of acute respiratory illness known as the COVID-19, which began to spread in the world very quickly.
V Yazdi Feyzabadi, R Amiri, M Seyedi
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Optimising dementia screening in community-dwelling older adults: A rapid review of brief diagnostic tools in Singapore [PDF]
Introduction: Timely detection of dementia enables early access to dementia-specific care services and interventions. Various stakeholders brought together to refine Singapore’s dementia care strategy identified a lack of a standardised cognitive ...
Yew Yoong Ding +10 more
core +1 more source
Frontiers in PsychiatryThis paper reports findings from a rapid literature review that informed new guidelines for conducting patient-oriented research in forensic mental health settings.
Christopher Canning +13 more
doaj +1 more source