Results 121 to 130 of about 1,834,579 (310)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Rapid Literature Review [PDF]

open access: yes
Rapid Literature ...
Maria Alcimar Meireles (10927794)
core   +1 more source

Methodological and reporting quality of systematic and rapid reviews on human mpox and their utility during a public health emergency

open access: yesCochrane Evidence Synthesis and Methods
Introduction Evidence syntheses were rapidly produced during the 2022 mpox outbreak despite a lack of studies. The aim of this methodological study was to assess the quality and utility of the evidence syntheses produced during the first 6 months of the ...
Kusala Pussegoda   +7 more
doaj   +1 more source

Recovery from gaming addiction: A thematic synthesis

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace
In recent years the field of gaming addiction has experienced an upsurge in empirical studies on various treatment approaches. Despite the advances in our understanding of how gaming addiction can be treated, the wider concept of recovery continues to ...
Ksenija Vasiljeva   +2 more
doaj   +1 more source

Evaluation of an HIV-specific rapid response service for community-based organisations in Ontario, Canada

open access: yesHealth Research Policy and Systems, 2019
Background To support AIDS service organisations and other community-based organisations’ use of research evidence to inform HIV-related programmes, services and policies, the Ontario HIV Treatment Network (OHTN) developed a Rapid Response Service.
Michelle Camilleri   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Rapid Situation Analysis: a hybrid, multi-methods, qualitative, participatory approach to researching tourism development phenomena [PDF]

open access: yes, 2010
This study develops a hybrid, bottom-up approach to field research, namely Rapid Situation Analysis, and implements it in Ghana. It draws on elements from two existing participatory methodological approaches: Rapid Rural Appraisal and Participatory ...
Koutra, Christina, Christina Koutra
core   +1 more source

Exploring the complexity of the implementation determinants of human papillomavirus vaccination in Africa through a systems thinking lens: A rapid review

open access: yesHuman Vaccines & Immunotherapeutics
A rapid review was conducted to explore the implementation determinants of human papillomavirus (HPV) vaccination in the World Health Organization African Region and describe their dynamic relationship.
Abdu A. Adamu   +3 more
doaj   +1 more source

Meta-Analytic Methodology for Basic Research: A Practical Guide

open access: yesFrontiers in Physiology, 2019
Basic life science literature is rich with information, however methodically quantitative attempts to organize this information are rare. Unlike clinical research, where consolidation efforts are facilitated by systematic review and meta-analysis, the ...
Nicholas Mikolajewicz   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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