Results 51 to 60 of about 10,159,491 (253)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Item - Test Alternate Title

Item - Test Description ...
Item - Test Creator 1, Item - Test Creator 3, Item - Test Creator 2   +2 more
core   +1 more source

Rapid Determination of SARS-CoV-2 antibodies using a bedside, point-of-Care, serological test

Emerging Microbes and Infections, 2020
Background: Several serological tests for SARS-CoV-2 have been developed or use, but most have only been validated on few samples, and none provide medical practitioners with an easy-to-use, self-contained, bedside test with high accuracy.
Laurent Dortet, Cecile Emeraud, Christelle Vauloup-Fellous, Mouna Khecharem, Jean-Baptiste Ronat, Nicolas Fortineau, Anne-Marie Roque-Afonso, Thierry Naas   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

DIAGNOSTIC PERFORMANCE OF A RAPID IN-CLINIC TEST FOR THE DETECTION OF FELINE PARVOVIRUS [PDF]

Assiut Veterinary Medical Journal
Feline parvovirus (FPV) is one of the most common causes of acute hemorrhagic enteritis, with high mortalities in kittens. As clinical diagnosis is often indecisive, the aim of our study was to evaluate the diagnostic accuracy of in-clinic rapid tests ...
MOHAMMED ABDELBAKY, KHALED EL-KHABAZ, MAHA HAMED   +2 more
doaj   +1 more source

A lateral flow immunoassay test performance in SARS-CoV-2 seroprevalence surveys: a validation study among healthcare workers

Emerging Microbes and Infections, 2020
The objective of this study was to evaluate the validity and reliability of NG-Test® when used as a finger-prick test on healthcare workers and to compare it to the ELISA Wantai Immunoassay.
Ronan Garlantézec, Christopher Heslan, Emilie Tadie, Pierre Tattevin, Vincent Thibault, Christophe Paris   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Effectiveness of Strongyloides Recombinant IgG Immunoreactive Antigen in Detecting IgG and IgG4 Subclass Antibodies for Diagnosis of Human Strongyloidiasis Using Rapid Immunochromatographic Tests

Diagnostics, 2020
Human strongyloidiasis is an important soil-transmitted helminthiasis that affects millions worldwide and can develop into fatal systemic strongyloidiasis in immunosuppressed patients.
Patcharaporn Boonroumkaew, Lakkhana Sadaow, Oranuch Sanpool, Rutchanee Rodpai, Tongjit Thanchomnang, Weeraya Phupiewkham, Pewpan M. Intapan, Wanchai Maleewong   +7 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Rapid generation of thermal-safe test schedules

, 2005
Overheating has been acknowledged as a major issue in testing complex SOCs. Several power constrained system-level DFT solutions (power constrained test scheduling) have been recently proposed to tackle this problem.
Rosinger, Paul, Chakrabarty, Krishnendu, Krishnendu Chakrabarty, Al-Hashimi, Bashir, Paul Rosinger, Bashir Al-hashimi   +5 more
core   +1 more source