Results 71 to 80 of about 10,159,491 (253)

Rapid Manufacturing of Patient-specific Shielding Masks, using RP in parallel with Metal Spraying

, 2005
Published ArticleThe purpose of the present work is to develop a methodology to manufacture patient‐specific models (lead masks) to be used as protective shields during cancer treatment, using 3D photography, rapid prototyping (RP) and metal spraying. It
Booysen, Gerrie J., Truscott, Michéle, de Beer, Deon J., Barnard, Ludrick J., van der Walt, Jakobus G.   +4 more
core  

Rapid detection of methicillin-resistant Staphylococcus aureus directly from clinical samples: methods, effectiveness and cost considerations

GMS German Medical Science, 2009
Methicillin-resistant Staphylococcus aureus (MRSA) isolates is a serious public health problem whose ever-increasing rate is commensurate with the pressure it is exerting on the healthcare system. At present, more than 20% of clinical S.
Stürenburg, Enno
doaj  

Evaluation of a rapid immunochromatographic diagnostic test (RIDT) for diagnosis of rabies in samples from Argentina

Journal of Infection in Developing Countries, 2018
Introduction: Rabies is a globally widespread zoonosis of viral origin that causes fatal encephalitis in humans and animals. In countries where rabies is endemic and there is a lack of well-equipped diagnostic laboratories, a rapid immunochromatographic
Federico Gury Dohmen, Esteban Kovacs, Natalia Elizabeth Prestrera, Fernando Javier Beltrán   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

High-throughput near-infrared spectroscopy for detection of major components and quality grading of peas

Frontiers in Nutrition
Pea (Pisum sativum L.) is a nutrient-dense legume whose nutritional indicators influence its functional qualities. Traditional methods to identify these components and examine the relationships between their contents could be more laborious, hindering ...
Jingwen Zhu, Guozhi Ji, Guozhi Ji, Bingyu Chen, Bangyu Yan, Feiyue Ren, Ning Li, Ning Li, Xuchun Zhu, Shan He, Zhishen Mu, Zhishen Mu, Hongzhi Liu   +12 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

An at-home and electro-free COVID-19 rapid test based on colorimetric RT-LAMP

Journal of Infection in Developing Countries
Introduction: In the fight against virus-caused pandemics like COVID-19, diagnostic tests based on RT-qPCR are essential, but they are sometimes limited by their dependence on expensive, specialized equipment and skilled personnel.
Diem Hong Tran, Hau Thi Tran, Trang Nguyen Minh Pham, Le Minh Bui, Huong Thi Thu Phung   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Point-of-care N-terminal pro-brain natriuretic peptide testing in patients with heart failure: data from the DREAM study

Российский кардиологический журнал
Aim. To compare the blood levels of N-terminal pro-brain natriuretic peptide (NTproBNP), determined using a Russian semi-quantitative point-of-care test and quantitative laboratory tests, depending on the presence and severity of heart failure (HF) and ...
F. I. Belyalov, N. G. Lozhkina, O. A. Shtegman, R. N. Yagudina, O. V. Kankharey, I. V. Reshina, E. E. Sergeeva, D. F. Belyalov, N. S. Belyalova, Z. Kh. Zhilokov, A. V. Aleynikova, E. A. Medvedeva, A. A. Kharitonov   +12 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source