Results 111 to 120 of about 554,532 (299)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

RAPID VARIATIONS OF OZONE ALTITUDE PROFILE OBSERVED WITH THE TUNABLE DIODE LASER HETERODYNE SPECTROMETER AT SYOWA STATION IN 1994

, 1997
P(論文)With the improved tunable diode laser heterodyne spectrometer (TDLHS-3), we observed stratospheric ozone, nitrous oxide, methane and nitric acid at Syowa Station (69.0′S, 39.6′E) from August 1994 to January 1995.
NAKANE, Hideaki, OKANO, Shoichi, TAGUCHI, Makoto, コイデ, ミチヒロ, ナカネ, ヒデアキ, フクニシ, ヒロシ, タグチ, マコト, KOIDE, Michihiro, FUKUNISHI, Hiroshi, オカノ, ショウイチ   +9 more
core   +1 more source

An in-depth analysis of a piece of shit : distribution of Schistosoma mansoni and hookworm eggs in human stool [PDF]

, 2012
BACKGROUND: An accurate diagnosis of helminth infection is important to improve patient management. However, there is considerable intra- and inter-specimen variation of helminth egg counts in human feces.
N'Goran Eliézer K., N'Goran, E. K., Krauth, Stefanie J., Knopp, S., Utzinger, Jürg, Coulibaly, Jean T., Jean T Coulibaly, Stefanie Knopp, Traoré, M., Utzinger Jürg, Jean T. Coulibaly (108845), Coulibaly Jean T., Jürg Utzinger, Krauth, S. J., Krauth Stefanie J., Stefanie J Krauth, Coulibaly, J. T., Eliézer K. N'Goran (108853), Utzinger, J., Jürg Utzinger (39609), Stefanie Knopp (108848), Stefanie J. Krauth (108843), Traoré Mahamadou, Eliézer K N'Goran, Traoré, Mahamadou, N'Goran, Eliézer, Mahamadou Traoré (108851), Knopp, Stefanie, Knopp Stefanie, Mahamadou Traoré   +29 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Rapid spectral variations of Be stars

, 1974
High time resolution observations of two Be stars ( K, Dra and ɣCas) have been made with an Image Isocon television camera in an attempt to detect rapid radial velocity and/or intensity variations of the Hydrogen emission lines.
Thompson, Harold Ian Bruce
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Simulation of Non-Stationary Mobile Underwater Acoustic Communication Channels Based on a Multi-Scale Time-Varying Multipath Model

Journal of Marine Science and Engineering
Traditional Underwater Acoustic Communication (UAC) typically assumes static or slowly varying channels over short observation periods and models multipath amplitude fluctuations with single-state statistical distributions. However, field measurements in
Honglu Yan, Songzuo Liu, Chenyu Pan, Biao Kuang, Siyu Wang, Gang Qiao   +5 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Sea surface temperatures of the western Arabian Sea during the last deglaciation. [PDF]

, 2007
In this study we present a sea surface temperature (SST) record from the western Arabian Sea for the last 20,000 years. We produced centennial-scale d18O and Mg/Ca SST time series of core NIOP929 with focus on the glacial-interglacial transition.
H. Elderfield, Jung, Simon, S. J. A. Jung, Greaves, M. J., Kroon, Dirk, Saher, M. H., D. Kroon, Jung, S. J. A., Kroon, D., M. J. Greaves, Jung, S.J.A., M. H. Saher, Saher, M.H., Elderfield, H., Greaves, M.J.   +14 more
core   +1 more source