Results 1 to 10 of about 88,141 (203)

The role of Raptor in lymphocytes differentiation and function

Frontiers in Immunology, 2023
Raptor, a key component of mTORC1, is required for recruiting substrates to mTORC1 and contributing to its subcellular localization. Raptor has a highly conserved N-terminus domain and seven WD40 repeats, which interact with mTOR and other mTORC1-related
Kamel Benlagha, Pamela Lee, Lu Yang
exaly   +3 more sources

RAPTOR promotes colorectal cancer proliferation by inducing mTORC1 and upregulating ribosome assembly factor URB1

Cancer Medicine, 2020
Mammalian target of rapamycin complex 1 (mTORC1) is evolutionally conserved and frequently activated in various tumors, including colorectal cancer (CRC).
Tian-Kang Guo
exaly   +2 more sources

Raptor/mTORC1 Acts as a Modulatory Center to Regulate Anti-bacterial Immune Response in Rockfish

Frontiers in Immunology, 2019
The mammalian target of rapamycin (mTOR) is an evolutionarily highly conserved atypical serine/threonine protein kinase, which regulates cell growth, proliferation, apoptosis, autophagy, and metabolism.
Xiumei Wei, Libin Zhang, Jialong Yang
exaly   +3 more sources

mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2

Nature Communications, 2016
The protein raptor is a subunit of the mTORC signalling complex. Here the authors show that Raptor also exists in a free form, unbound to mTORC, and that this free Raptor negatively regulates hepatic Akt activity and lipid metabolism in mice via a ...
KyeongJin Kim, Li Qiang, Utpal B Pajvani
exaly   +2 more sources

Comparative analysis of the fecal microbiota of healthy and injured common kestrel (Falco tinnunculus) from the Beijing Raptor Rescue Center [PDF]

PeerJ, 2023
The gut microbiota is a complex ecosystem that interacts with many other factors to affect the health and disease states of the host. The common kestrel (Falco tinnunculus) is protected at the national level in China.
Yu Guan, Lei Bao, Lei Zhou, Chang Dai, Zhisai Li, Shuai Zhang, Yugang Shang, Wenhui Niu, Yizhuo Zhang, Hongfang Wang   +9 more
doaj   +2 more sources

Thirteen Years of Counting Raptor Migration in Batumi: Observations and Their Importance for Raptor Conservation in Russia

Пернатые хищники и их охрана, 2022
Since 2008 Batumi Raptor Count (BRC) project has been monitoring autumn migration of birds of prey in the eastern African-Palearctic flyway in southwest Georgia on the eastern coast of the Black Sea.
Olga Zaytseva, Bart Hoekstra, Johannes Jansen, Dries Engelen, Folkert de Boer, Rafa Benjumea, Jasper Wehrmann, Simon Cavaillès, Triin Kaasiku, Diego Jansen, Pia Fetting, Aki Aintila, Wouter Vansteelant   +12 more
doaj   +1 more source

Thirteen Years of Counting Migration in Batumi: Observations and Their Importance for Raptor Conservation in Russia

Пернатые хищники и их охрана, 2023
One of the most important autumn migration bottlenecks for birds of prey in the Western Palearctic is situated in South-Western Georgia, between the east coast of the Black Sea and the range of Lesser Caucasus.
Olga O. Zaitseva, Bart Hoekstra, Wouter Vansteelant   +2 more
doaj   +1 more source

Breeding Phenology of Red-Shouldered Hawks (Buteo lineatus) Is Related to Snow Cover and Air Temperature During the Pre-Laying Period

Frontiers in Ecology and Evolution, 2021
Global climate change has advanced the breeding phenology of many avian species. However, raptors’ breeding phenologies may not respond in the same way to the factors that influence passerine breeding dates.
Cheryl R. Dykstra, Jeffrey L. Hays, Melinda M. Simon, Ann R. Wegman   +3 more
doaj   +1 more source

Glucagon-like peptide-1 receptor activation stimulates PKA-mediated phosphorylation of Raptor and this contributes to the weight loss effect of liraglutide

eLife, 2023
The canonical target of the glucagon-like peptide-1 receptor (GLP-1R), Protein Kinase A (PKA), has been shown to stimulate mechanistic Target of Rapamycin Complex 1 (mTORC1) by phosphorylating the mTOR-regulating protein Raptor at Ser791 following β ...
Thao DV Le, Dianxin Liu, Gai-Linn K Besing, Ritika Raghavan, Blair J Ellis, Ryan P Ceddia, Sheila Collins, Julio E Ayala   +7 more
doaj   +1 more source

Placental DEPTOR as a stress sensor during pregnancy [PDF]

, 2011
The author(s) has paid for this article to be freely available under the terms of the Creative Commons Attribution Non-Commercial Licence (http://creativecommons.org/licenses/by-nc/2.5/) which permits unrestricted non-commercial use, distribution and ...
Gidron, Y, Goumenou, A, Karteris, E, Mparmpakas, D, Zachariades, E   +4 more
core   +2 more sources