Results 101 to 110 of about 57,200 (265)

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

Non‐Invasive Scalp Tape‐Strip RNA Sequencing Captures Disease Activity and Treatment‐Response Signatures in Alopecia Areata

Allergy, EarlyView.
Non‐invasive scalp tape‐strip RNA sequencing captures core immune and follicular molecular signatures in alopecia areata. Tape‐strip transcriptomic profiles reflect disease severity and treatment response to baricitinib, with concordance to scalp biopsy‐derived signatures.
Carmen Mochón‐Jiménez, Jesús Gay‐Mimbrera, Viviana Dávila‐Flores, Helen He, Jerry Zhou, Irene Rivera‐Ruiz, Pedro J. Gómez‐Arias, Juan de Luque‐Fernández, Benjamin Ungar, Emma Guttman‐Yassky, Juan Ruano   +10 more
wiley   +1 more source

Navigating Oral Food Challenges in Clinical Trials to Keep the Science Moving Forward

Allergy, EarlyView.
ABSTRACT The oral food challenge (OFC) has long been the reference standard for food allergy diagnosis, as well as to confirm natural development of oral tolerance. The utilization of OFCs has significantly broadened from its role in defining disease to defining participant eligibility, individual allergen reactivity thresholds and treatment outcomes ...
Edwin H. Kim, J. Andrew Bird, Helen A. Brough, David M. Fleischer, Stacie M. Jones, Ildiko Kun, Wayne Shreffler, Claire Van Eenwyk, Brian P. Vickery, Julie Wang, Alexandra F. Santos   +10 more
wiley   +1 more source

Divergent Paths: A Comprehensive Review of Mechanisms and Clinical Implications in Atopic Dermatitis and Psoriasis

Allergy, EarlyView.
ABSTRACT Atopic dermatitis and psoriasis are two common cutaneous chronic inflammatory diseases. Although they share similar immunological mechanisms, their clinical implications in the patient are different. This review compares both diseases from different points of view such as genetics, natural history, triggers of disease, and skin barrier defects
Tali Czarnowicki, Kazunari Sugita, Zenas Yiu, Sandra Díez‐Ribas, Irene Garcia‐Jimenez, Emma Guttman‐Yassky, Luis F. Santamaria‐Babí   +6 more
wiley   +1 more source

IgE Antibody Function and Mast Cell Activation to Egg in Children Undergoing Baked and Loosely Cooked Egg Challenges

Allergy, EarlyView.
MAT is dependent on the presence of allergen‐specific IgE and can provide false‐negative results in allergic patients with low allergen‐specific IgE levels. MAT and BAT are moderately correlated. MAT can be used as a surrogate of BAT, when fresh blood is not available or in the case of patients with non‐releaser basophils.
Vikki Houghton, Vasco Claro, Nur Romli, Zainab Jama, Grammatiki Antoneria, Matthew Kwok, Alexandra F. Santos   +6 more
wiley   +1 more source

Emollient Formulations and Skin Barrier Practices in the Context of Eczema and Food Allergy Prevention

Allergy, EarlyView.
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj, Donald Y. M. Leung, Carina Venter, Barbara Sozańska, Helen A. Brough   +4 more
wiley   +1 more source

Morphology of Guard Hairs in Amazonian Marsupials: Intergeneric Variation, Habitat and Habit Association in a Phylogenetic Framework of the Order Didelphimorphia

Acta Zoologica, EarlyView.
ABSTRACT The cuticle and medulla of guard hairs exhibit distinct morphological patterns among mammalian species. To investigate this variability in marsupials from the Brazilian Amazon, we analysed guard hairs from nine Didelphimorphia species and incorporated data from an additional 25 didelphid species.
Matheus M. Bitencourt, Ana Cristina Mendes‐Oliveira, Gleomar F. Maschio, Maria Clara S. Ribeiro, Alexandra M. R. Bezerra   +4 more
wiley   +1 more source

Prevalence and Sociodemographic Variation of Allergic Diseases in Australia: Findings From the Australian National Health Survey

Clinical &Experimental Allergy, EarlyView.
Using data from 17,093 participants in the 2022 Australian National Health Survey, this study is the first to report nationwide prevalence estimates for allergic rhinitis (23.9%), food allergy (7.0%), drug allergy (5.2%), eczema (1.6%) and diagnosed asthma (10.8%) across Australia.
Yichao Wang, Jennifer J. Koplin, Janet M. Davies, Constance H. Katelaris, Debra J. Palmer, Jason A. Trubiano, Joy Lee, Michaela Lucas, Michael O′Sullivan, Sandra Vale, Sheryl van Nunen, Troy Wanandy, Dianne E. Campbell, Kirsten P. Perrett, Rachel L. Peters   +14 more
wiley   +1 more source

Constructed value of information with iterative scoring and parametric uncertainty to identify management‐relevant research priorities for a declining raptor species

Conservation Biology, EarlyView.
Abstract Constructed value of information (CVoI) is an expert elicitation decision‐analytic tool used to prioritize sources of uncertainty based on their potential to improve decision outcomes if resolved. Despite increased application of CVoI, the robustness of CVoI prioritization of sources of uncertainty relative to differences in expert elicitation
Kristin P. Davis, Mitchell J. Eaton, Emily R. Bjerre, Hillary M. White, Clint W. Boal, Jennifer H. Herner‐Thogmartin, Orin J. Robinson, Abigail J. Lawson   +7 more
wiley   +1 more source

Identifying the exposure of taxonomic, functional, and phylogenetic diversity of steppe birds to renewable energy development

Conservation Biology, EarlyView.
Abstract Biodiversity is globally threatened by human impacts, including land‐use transformation and climate change, which has prompted a rapid transition from fossil fuels to cleaner energy sources, such as photovoltaic (PV) energy. However, utility‐scale PV plants require vast areas and can lead to conflicts with biodiversity conservation, making ...
Pablo Medrano‐Vizcaíno, François Mougeot, Beatriz Arroyo, Gerard Bota, David Giralt, Laura Maeso‐Pueyo, Carlos A. Martín, Manuel B. Morales, Pedro P. Olea, Juan Traba, Ana Benítez‐López   +10 more
wiley   +1 more source