In adults with moderate AD post‐TCS and ‐TCI, who may otherwise be eligible for systemic therapy, 1.5% ruxolitinib cream improved clinical signs and symptoms in the TRuE‐AD4 study. Abstract Background In patients with moderate atopic dermatitis (AD), topical corticosteroids (TCS) and topical calcineurin inhibitors (TCI) often do not sufficiently ...
José Manuel Carrascosa +14 more
wiley +1 more source
Loss of the Mechanistic Target of Rapamycin Complex 1 Causes a Lethal Alpha-1 Antitrypsin Deficiency-Associated Liver Disease. [PDF]
Bewersdorf L +16 more
europepmc +1 more source
Radiation oncology at a new frontier: Hotspots, challenges, and emerging advances. [PDF]
Wei B, Zhang Z, Chen D, Yu J.
europepmc +1 more source
Management of chronic urticaria: Current status and future prospect
Chronic urticaria is driven by mast cell activation through autoimmune, inflammatory, and neuroimmune pathways. A structured approach combining diagnosis, patient‐reported outcomes, stepwise therapy, treatment optimization, monitoring and emerging targeted agents may improve disease control and enable more personalized management.
Andaç Salman +15 more
wiley +1 more source
Scalable nanofocusing heterojunctions for raptor-inspired on-chip vision perception. [PDF]
Qin L +16 more
europepmc +1 more source
The pectoralis muscle orientation as an indicator of the modes of wing‐propelled locomotion in birds
The pectoralis orientation of birds was consistent with the orientation of the aerodynamic force acting on the wing, varying by wing‐propelled locomotion (WPL) mode. The skeletal morphology unique to each WPL mode, related to the origin/insertion of the pectoralis, may be associated with these functional demands of pectoralis orientation.
Takumi Akeda, Shin‐ichi Fujiwara
wiley +1 more source
Endangered Steppe Eagle (<i>Aquila nipalensis</i>) (Aves, Accipitriformes, Accipitridae) genome and mitogenome assembly: A resource for molecular evolution and comparative genomics. [PDF]
Buthasane W +10 more
europepmc +1 more source
Tuberous sclerosis complex 2 association with RelA/p65 is critical for NF-κB activation and endothelial cell inflammation. [PDF]
Tahir I, Najar RA, Rahman A.
europepmc +1 more source
Advocacy and the function of folk psychology
Why do we care about getting mental state attributions right? A common answer is that folk psychology is a proto‐scientific theory that allows us to predict and explain the behavior of physical systems. I argue that this position is inconsistent with one of the central practices in which attribution of desire occurs: to advocate for our interests and ...
Henry Schiller
wiley +1 more source
Molecular mechanisms underlying the ameliorative effects of crocodile head-derived bioactive peptides on DEX-induced muscle atrophy: insights from proteomics and gut microbiota analysis. [PDF]
Song H, Yan L, Zhao W, Yu Z.
europepmc +1 more source

