Bimekizumab 2‐year efficacy by hidradenitis suppurativa duration: BE HEARD EXT results
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Raj Chovatiya +9 more
wiley +1 more source
Orchard netting impacts on biodiversity leading to cascading effects at the ecosystem level
ABSTRACT Agriculture must ensure food production without further compromising the ecosystem functions upon which it depends. Agricultural practices should therefore avoid harming farmland biodiversity, especially of taxa that supply the key ecosystem services (e.g.
Corrado Alessandrini +13 more
wiley +1 more source
Genetically targeted mTORC1 inhibitor reveals transcriptional control by nuclear mTORC1. [PDF]
Zhong Y +9 more
europepmc +1 more source
Conformational ensembles of the disordered 4E‐BP2:eIF4E complex restrained by smFRET experiments
Abstract Eukaryotic cap‐dependent translation initiation is regulated by binding of the predominantly folded eukaryotic initiation factor 4E (eIF4E) to the intrinsically disordered eIF4E binding proteins (4E‐BPs). Here, we report full‐length atomistic conformational ensembles generated by IDPConformerGenerator and optimized by X‐EISDv2 workflow for ...
Spencer Smyth +5 more
wiley +1 more source
Induced triple clutching in captivity for three falcon species: Common Kestrel (<i>Falco tinnunculus</i>), Saker Falcon (<i>Falco cherrug</i>) and Peregrine Falcon (<i>Falco peregrinus</i>). [PDF]
Petrov R, Valchev A.
europepmc +1 more source
ABSTRACT The cuticle and medulla of guard hairs exhibit distinct morphological patterns among mammalian species. To investigate this variability in marsupials from the Brazilian Amazon, we analysed guard hairs from nine Didelphimorphia species and incorporated data from an additional 25 didelphid species.
Matheus M. Bitencourt +4 more
wiley +1 more source
TORC1-dependent translation drives chromatin remodeling during the germ-cell-to-maternal transition in Drosophila. [PDF]
Kotb NM +6 more
europepmc +1 more source
PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad +2 more
wiley +1 more source
Ad-VT oncolytic adenovirus suppresses bladder cancer via cAMP-dependent AMPK-Raptor activation and G2/M arrest. [PDF]
Li D +8 more
europepmc +1 more source
Theologies of Mind: Eriugena and Pratyabhijñā Śaivism
Abstract Though Eriugena's affinities with several Hindu traditions are clear, this article offers to my knowledge the first detailed discussion of Eriugena's theology in relation to any Indic theological school, here, the nondualist Śaiva tradition known as the Pratyabhijñā (“Recognition”) lineage.
Matthew Z. Vale
wiley +1 more source

