Results 61 to 70 of about 3,259,058 (349)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Analysis of temperature characteristics of power transformer withstand short circuit shock for two seconds

open access: yesEnergy Reports, 2023
The occurrence of a short-circuit fault in a transformer results in a rapid increase in the short-circuit current, and the temperature of the transformer winding rises rapidly.
Junyang Wang   +5 more
doaj   +1 more source

Anisotropic electrical and thermal magnetotransport in the magnetic semimetal GdPtBi

open access: yes, 2020
The half-Heusler rare-earth intermetallic GdPtBi has recently gained attention due to peculiar magnetotransport phenomena that have been associated with the possible existence of Weyl fermions, thought to arise from the crossings of spin-split conduction
Abdel-Haq, Wajdi   +16 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

An analysis on chain characteristics of highstand geological disasters in high mountains and extremely high mountains based on optical remote sensing technology:A case study of representative large landslides in upper reach of Jinsha River

open access: yesZhongguo dizhi zaihai yu fangzhi xuebao, 2021
The upper reaches of Jinsha River are typical high mountain canyon areas with strong terrain cutting and deep valleys. Affected by the Jinsha River fault zone, the slope integrity is poor and the rock mass is fragmented, which makes the mountain ...
Wen LIU   +7 more
doaj   +1 more source

THE SEPARATION OF THE RARE EARTHS.

open access: yesJournal of the American Chemical Society, 1912
n ...
openaire   +2 more sources

Numerical Testing of The Rare Earth Hypothesis using Monte Carlo Realisation Techniques

open access: yes, 2010
The Search for Extraterrestrial Intelligence (SETI) has thus far failed to provide a convincing detection of intelligent life. In the wake of this null signal, many "contact pessimistic" hypotheses have been formulated, the most famous of which is the ...
Annis   +14 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Rare Earths.

open access: yesScience (New York, N.Y.), 1916
n ...
openaire   +2 more sources

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