Results 71 to 80 of about 3,349,140 (303)
Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder [PDF]
, 2015 Genetic risk prediction has several potential applications in medical research and clinical practice and could be used, for example, to stratify a heterogeneous population of patients by their predicted genetic risk.Caesar, Sian, Strohmaier, Jana, Wray, Naomi R., Wiersma D., Puri, Vinay, McGough J. J., Collier, David A., Myin-Germeys, Inez, Absher D., Chen, G. B., Loo, Sandra K., Wijsman E. M., Hallmayer, Joachim, Berrettini, Wade, Paterson A. D., Black D. W., Lathrop, Mark, Leboyer, Marion, Craddock, Nicholas, Lee, S Hong; id_orcid, Maier, R., Pato, Carlos N., Coryell W. H., Franke B., Datta S., Smalley, Susan L., Hansen, Thomas F., Zhang, Peng, Parr JR, Moser G., Santangelo S. L., Pericak-Vance M. A., Mühleisen, Thomas W., Van Os, Jim, Holmans, Peter Alan, Madden P. A. F., Hakonarson, Hakon, Nyholt, Dale R., Krabbendam, Lydia, Moser, Gerhard, State, Matthew, Landen M, De Geus E. J., Roeyers H., Freedman, Robert, Kent, Lindsey, Klauck S. 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L., Cichon, Sven, Ribasés, Marta, Coryell W, Lord, Catherine, Wray, N.R., Zammit S., Kirov, George, Nikolov, Ivan, Penninx, Brenda W., Schulze, Thomas G., Todorov, Alexandre A., Cuccaro, Michael L., Keller M. C., Sanders, Alan R., Bass N., Sullivan, Patrick F., Moskvina, Valentina, Oades, Robert D., St Clair, David, Freimer, Nelson B., Bunney, William E., Lee P. H., Byerley, William F., Moser G, Arking, Dan E., Mane, Shrikant M., Weiss L. A., O'Dushlaine C., Lee, Phil H., Smoller J. W., Rice J. P., Absher, Devin, Choudhury K., Craig, Ian, Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Scheftner WA, Chen G. -B., Pimm, Jonathan, Smoller, Jordan, Linszen, Don H., Wienker, Thomas F., Koller, Daniel L., Müller-Myhsok, Bertram, Scheftner, W.A., Ferrier, I. Nicol, Loo S. K., Liu C., Slager, Susan L., Byerley W. F., Maestrini E., Ennis, Sean, Paterson, Andrew D., Breuer R., Lee, S. 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A., Buitelaar J. K., Schumacher, Johannes, Ophoff R. A., Scott Stroup T., Buitelaar, Jan K., Potash JB, Uhr, Manfred, Meier S., Meier, Sandra, Korszun A., Breuer, René, Bloss, Cinnamon S., Montgomery, Grant W., Smoller, Jordan W., Anney, Richard, Weissman, Myrna, Murtha, Michael, De Haan, Lieuwe, Gordon-Smith K., Quinn, Emma M., Nelson S. F., Hoogendijk, Witte J., Degenhardt, Franziska, Lowe J. K., Rothenberger A., Quested, Digby J., Barrett T. B., Oades R. D., Devlin B., Szatmari P., Asherson, Philip; id_orcid, Nolen, Willem A., Knowles, James A., Grozeva D., Vieland, Veronica J., Thompson R. C., Gejman P. V., De Haan L., Vicente A. M., Perlis R. H., Knowles J. A., Freitag, Christine M., Hautzinger M., Nyholt D. R., Bruggeman, Richard, Ramos-Quiroga J. A., McInnis M. 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M., Melle, Ingrid, Myers, Richard M., Chen, Guo-Bo, Boomsma, D.I.; id_orcid, Rossin, Lizzy, O'Donovan M. C., Poustka F., Crosbie J., Curtis D., Greenwood, Tiffany A., Bailey, Anthony J., Henders A. K., Zammit, Stanley, Friedl, Marion, O’Dushlaine, Colm, Owen, Michael John, Zitman, Frans G., Bloss C. S., Lewis C. M., Buxbaum J. D., Bauer M., Casas, Miguel, McGrath, Patrick J., Bailey A. J., Pergadia M. L., Morken, Gunnar, Levinson, Douglas F, Lee, S.H., Betancur, Catalina, Walsh C. A., Weissman M. M., Steffens M., Mane S. M., Muller-Myhsok B., Nothen M. M., Monaco A. P., Fombonne, Eric, Roeyers, Herbert, Agartz, Ingrid, Rehnstrom K., Weiss, Lauren A., Bettecken T., Strohmaier J., Schatzberg, Alan F., Reif A., Ripke, S., Rothenberger, Aribert, Schork N. J., Shi J, Poustka, Fritz, Wray, N. R., Lee S. H., Gallagher, Louise, Smoller JW, Weissmann, M.M., Kandaswamy R., Levinson, Douglas F., Gordon S. D., Parr, Jeremy R., Lieberman, Jeffrey A., Willemsen, G., Kennedy J. L., Cross-Disorder Working Group of the Psychiatric Genomics, Consortium., Sklar P., Barnes, Michael R., Boomsma, D.I., Lawson W. B., Meng, Fan, Smoller, Jordan W, Osby U., Akil, Huda, McGough, James J., Shi J., Jones, Ian, Muhleisen T. W., Matthews, Keith, Strauss J. S., Haines J. L., Mattingsdal M., Geschwind, Daniel H., Herms S., Sergeant J. A., Oliveira, Guiomar, Nwulia, Evaristus A., Ruderfer D., Battaglia, Agatino, McInnis, Melvin G., Berrettini W., Dudbridge F., Pickard B. S., McGuffin, Peter, McCarroll, Steven A., Bunney W. E., Kim Y., McLean A. W., Crosbie, Jennifer, Heath, Andrew C., Blackwood, Douglas H.R., Fanous, Ayman, Moser, G, Coryell, W, Hultman, CM, Scheftner, WA, Lencz, T., Weissman, MM, +7 additional authors, Smoller, J., Chen, G-B, Potash, JB, Maier, R, Shi, J +858 morecore +3 more sourcesTranslophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura +11 morewiley +1 more sourceMetastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano +2 morewiley +1 more source
