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Physical Therapy, 1999 Multiple system atrophy is a neurological disorder that has gone unrecognized for too long due to its involvement across multiple regions of the central nervous system. This disorder is finally being unveiled through increased reporting in the scientific literature.
Laurie Swan, Jérôme Dupont
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Bereitschaftspotential in Multiple System Atrophy [PDF]
Frontiers in Neurology, 2021 Objective: Multiple system atrophy (MSA) is a neurodegenerative disorder manifesting as parkinsonism, cerebellar ataxia, and autonomic dysfunction. It is categorized into MSA with predominant parkinsonism (MSA-P) and into MSA with predominant cerebellar ...
Yi-Chien Yang +16 more
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FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy. [PDF]
PLoS ONE, 2013 Multiple system atrophy is a parkinsonian neurodegenerative disorder. It is cytopathologically characterized by accumulation of the protein p25α in cell bodies of oligodendrocytes followed by accumulation of aggregated α-synuclein in so-called glial ...
Christine L Kragh +12 more
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Posterior fossa arachnoid cysts in multiple system atrophy [PDF]
IBRO Neuroscience ReportsBackground: Multiple system atrophy (MSA) is an α-synucleinopathy characterized by prominent cerebellar or parkinsonian features. This is pathologically due to the deposition of α-synuclein in glial cells, the mechanism by which s not entirely clear.
Audrey M. Blazek Ramsay, M.D +3 more
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Acoustic Characteristics of Stridor in Multiple System Atrophy. [PDF]
PLoS ONE, 2016 Nocturnal stridor is a breathing disorder prevalent in patients with multiple system atrophy (MSA). An improved understanding of this breathing disorder is essential since nocturnal stridor carries a poor prognosis (an increased risk of sudden death). In
Dae Lim Koo +4 more
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Postgraduate Medical Journal, 2001 Multiple system atrophy (MSA) is a degenerative disease of the central nervous system. Dejerine and Thomas in 1900 were the first to use the term olivopontocerebellar atrophy (OPCA) in two sporadic cases,1 although Menzel described the first case in 1891.
G K, Wenning +4 more
+7 more sources
Inflammation in multiple system atrophy
Frontiers in Immunology, 2023 Misfolding protein aggregation inside or outside cells is the major pathological hallmark of several neurodegenerative diseases. Among proteinopathies are neurodegenerative diseases with atypical Parkinsonism and an accumulation of insoluble fibrillary ...
Marta Leńska-Mieciek +5 more
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Multiple system atrophy: diagnostic methods and biomarkers [PDF]
Анналы клинической и экспериментальной неврологии, 2022 Multiple system atrophy (MSA) is a neurodegenerative disease belonging to a group of synucleinopathies and characterized by significant autonomic failure, parkinsonian syndrome, and cerebellar signs.
Maksim N. Andreev +1 more
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S.S. Korsakov Journal of Neurology and Psychiatry, 2023 The article presents a progressive neurodegenerative disease — multisystem atrophy, characterized by a combination of autonomic failure and various motor disorders, including parkinsonism and/or cerebellar ataxia; etiopathogenetic factors and variants of the clinical picture are described.
M.P. Topuzova +8 more
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Frontiers in Neurology, 2022 Multiple system atrophy (MSA) is a rare and progressive neurodegenerative disorder. Autonomic failure (AF) is one main clinical feature which has a significant impact on health-related quality of life.
Marc Kermorgant +13 more
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