Results 21 to 30 of about 221,497 (291)

DISTRIBUTION OF NEURONAL CYTOPLASMIC INCLUSIONS IN MULTIPLE SYSTEM ATROPHY [PDF]

, 1995
1995-12-25Neuronal cytoplasmic inclusions (NCls) were demonstrated by means of silver staining (Gallyas staining) in the central nervous systems of 18 deceased patients with multiple system atrophy (MSA) - 6 with olivopontocerebellar atrophy (OPCA), 6 ...
TAKAHASHI, AKIRA, SUGIURA, KENICHI, HASHIZUME, YOSHIO, KUME, AKITO   +3 more
core   +1 more source

A Case of Multiple System Atrophy (MSA) – First Presentation in a Psychiatry Service

, 2021
A 67 years old female developed cognitive deficits, depression and anxiety as first symptoms of multiple system atrophy (MSA). In the course of an year autonomic failure, parkinsonism and cerebellar ataxia also developed.
Andra Livia BRONESCU, Elena Alina ROSCA, Ovidiu Iulian TUDOR   +2 more
core   +1 more source

Heterogeneity of Multiple System Atrophy: An Update

Biomedicines, 2022
Multiple system atrophy (MSA) is a fatal, rapidly progressing neurodegenerative disease of uncertain etiology, clinically characterized by various combinations of Levodopa unresponsive parkinsonism, cerebellar, autonomic and motor dysfunctions.
Kurt A. Jellinger
doaj   +1 more source

Models of multiple system atrophy [PDF]

Experimental & Molecular Medicine, 2019
AbstractMultiple system atrophy (MSA) is a neurodegenerative disease with diverse clinical manifestations, including parkinsonism, cerebellar syndrome, and autonomic failure. Pathologically, MSA is characterized by glial cytoplasmic inclusions in oligodendrocytes, which contain fibrillary forms of α-synuclein.
Lee, He-Jin, Ricarte, Diadem, Ortiz, Darlene, Lee, Seung-Jae   +3 more
openaire   +2 more sources

Dystonia in multiple system atrophy [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2002
To delineate the frequency and nature of dystonia in multiple system atrophy (MSA).A cohort of 24 patients with clinically probable MSA over the past 10 years were prospectively followed up. Motor features were either dominated by parkinsonism (MSA-P subtype, n=18) or cerebellar ataxia (MSA-C, n=6). Classification of dystonic features and their changes
S M, Boesch, G K, Wenning, G, Ransmayr, W, Poewe   +3 more
openaire   +2 more sources

The genetic basis of multiple system atrophy

Journal of Translational Medicine, 2023
Multiple system atrophy (MSA) is a heterogenous, uniformly fatal neurodegenerative ɑ-synucleinopathy. Patients present with varying degrees of dysautonomia, parkinsonism, cerebellar dysfunction, and corticospinal degeneration.
Fan Shuen Tseng, Joel Qi Xuan Foo, Aaron Shengting Mai, Eng-King Tan   +3 more
doaj   +1 more source

Multiple system atrophy cerebellar variant: pathological implications of the neural connectivity

, 2023
Introducción. La atrofia multisistémica (MSA) es una enfermedad neurodegenerativa progresiva que afecta principal mente la materia blanca (WM, por su sigla en inglés). Este tipo de atrofia se caracteriza por ocasionar inclusiones cito plasmáticas gliales
Sandoval Traslaviña, Karen, Guardias Garzon, Juan Andres, Caceres Urbano, Laura Daniela, Leon Malkun, Luis Alejandro, Huerfano Tamaro, Nataly Andrea, Gutiérrez Huertas, Jessica Liliana   +5 more
core   +1 more source

Multiple Sistem Atrophy: Sebuah Laporan Kasus

Aksona, 2021
Pendahuluan: Multiple sistem atrophy adalah penyakit degeneratif yang dapat menyebabkan kecacatan bahkan kematian. Sedikit jurnal yang yang membahas tentang diagnosis dan penanganan multiple system atrophy secara menyeluruh.
Edfina Rahmarini, Muhammad Hamdan, Priya Nugraha, Paulus Sugianto, Yudha Haryono   +4 more
doaj   +1 more source

Somatic copy number gains of α-synuclein (SNCA) in Parkinson's disease and multiple system atrophy brains [PDF]

, 2018
The α-synuclein protein, encoded by SNCA, has a key role in the pathogenesis of Parkinson's disease and other synucleinopathies. Although usually sporadic, Parkinson's disease can result from inherited copy number variants in SNCA and other genes.
Jan-Willem Taanman, Tammaryn Lashley, Helen Ling, Nacheva, E, Pease, Daniel, Lashley, Tammaryn, Katya Mokretar, Henry Houlden, Christos Proukakis, Mokretar, Katya, Schapira, AHV, Ling, Helen, Soenmez, A, Lashley, T, Schapira, Anthony HV, Proukakis, C, Ayesha Ejaz, Proukakis, Christos, Houlden, H, Anthony H V Schapira, Steve Gentleman, Soenmez, Aynur, Gentleman, Steve, Taanman, Jan-Willem, Janice L Holton, Gentleman, S, Pease, D, Ejaz, A, Ejaz, Ayesha, Holton, Janice L, Aynur Soenmez, Houlden, Henry, Nacheva, Elizabeth, Holton, JL, Elizabeth Nacheva, Taanman, J-W, Ling, H, Mokretar, K, Daniel Pease   +38 more
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Implanted System for Orthostatic Hypotension in Multiple-System Atrophy

, 2022
Orthostatic hypotension is a cardinal feature of multiple-system atrophy. The upright posture provokes syncopal episodes that prevent patients from standing and walking for more than brief periods.
Schoettker, P., Asboth, Leonie, Asboth, L., Berney, Maxime, Allenbach, G., Becce, F., Amir, Suje, Wuerzner, G., Bally, J.F., Paley, Aurelie, Demesmaeker, R., Courtine, G., Hankov, Nicolas, Jimenez, Mayte Castro, Paley, A., Hankov, N., Amir, S., Bally, Julien F., Courtine, Gregoire, Squair, J.W., Schoettker, Patrick, Becce, Fabio, Hernandez-Charpak, S., Squair, Jordan W., Dumont, Gregory, Allenbach, Gilles, Berney, M., Hernandez-Charpak, Sergio, Castro Jimenez, M., Demesmaeker, Robin, Bloch, J., Dumont, G., Bloch, Jocelyne, Wuerzner, Gregoire   +33 more
core   +1 more source