Results 21 to 30 of about 354,264 (324)

Heterogeneity of Multiple System Atrophy: An Update

Biomedicines, 2022
Multiple system atrophy (MSA) is a fatal, rapidly progressing neurodegenerative disease of uncertain etiology, clinically characterized by various combinations of Levodopa unresponsive parkinsonism, cerebellar, autonomic and motor dysfunctions.
Kurt A. Jellinger
doaj   +1 more source

EVIDENCE FOR "UNER TAN SYNDROME" AS A HUMAN MODEL FOR REVERSE EVOLUTION [PDF]

, 2006
“Uner Tan Syndrome” was further studied in a second family. There was no cerebellar atrophy, except a mild vermial atrophy in MRI scans of the affected individuals. This is not, however, the pathogenesis of the “Uner Tan Syndrome”, since in the first and
Tan, Prof. Dr. Uner
core   +1 more source

Is Dysphagia in Multiple System Atrophy Responsive to Levodopa? Results from a Retrospective Study. [PDF]

Mov Disord Clin Pract
Gandor F, Berger L, Jäger V, Demmin K, Gruber D, Schimming K, Thimm P, Ebersbach G, Schreiber S, Rowe D, Vogel A.   +10 more
europepmc   +3 more sources

Clinical characteristics of multiple system atrophy in Serbian population [PDF]

, 2006
Background/Aim. Mulstiple system atrophy (MSA) is a neurodegenerative central nervous system disorder, characterized by any combination of extrapyramidal, cerebellar, pyramidal or autonomic disturbance.
Dragašević Nataša, Kostić Vladimir, Nešić Nada, Pekmezović Tatjana, Ribarić Ksenija, Svetel Marina   +5 more
core   +1 more source

The genetic basis of multiple system atrophy

Journal of Translational Medicine, 2023
Multiple system atrophy (MSA) is a heterogenous, uniformly fatal neurodegenerative ɑ-synucleinopathy. Patients present with varying degrees of dysautonomia, parkinsonism, cerebellar dysfunction, and corticospinal degeneration.
Fan Shuen Tseng, Joel Qi Xuan Foo, Aaron Shengting Mai, Eng-King Tan   +3 more
doaj   +1 more source

Multiple Sistem Atrophy: Sebuah Laporan Kasus

Aksona, 2021
Pendahuluan: Multiple sistem atrophy adalah penyakit degeneratif yang dapat menyebabkan kecacatan bahkan kematian. Sedikit jurnal yang yang membahas tentang diagnosis dan penanganan multiple system atrophy secara menyeluruh.
Edfina Rahmarini, Muhammad Hamdan, Priya Nugraha, Paulus Sugianto, Yudha Haryono   +4 more
doaj   +1 more source

Multiple system atrophy-cerebellar: A case report and literature review

Radiology Case Reports, 2023
We reported a case of a 48-year-old female patient admitted to the hospital due to balance disorder which progressed rapidly within 1 week. Cerebral magnetic resonance imaging showed significant atrophy and hyperintensities at the middle cerebellar ...
Thi Thuong Doan, MD, Thuy Dung Pham, MD, Duy Duan Nguyen, MD, Dac Hong An Ngo, MD, Trong Binh Le, MD, PhD, Thanh Thao Nguyen, MD, PhD   +5 more
doaj   +1 more source

Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy. [PDF]

, 2015
BackgroundMultiple system atrophy (MSA) is a neurodegenerative disease characterized by parkinsonism, ataxia and dysautonomia. Histopathologically, the hallmark of MSA is the abnormal accumulation of alpha-synuclein (α-syn) within oligodendroglial cells,
Adame, Anthony, Mandler, Markus, Mante, Michael, Masliah, Eliezer, Mattner, Frank, Patrick, Christina, Rockenstein, Edward, Santic, Radmila, Schmidhuber, Sabine, Schmidt, Walter, Schneeberger, Achim, Valera, Elvira, Weninger, Harald   +12 more
core   +2 more sources

Asymmetrical putaminal atrophy in parkinsonism-predominant multiple system atrophy (MSA-P): A case report

Radiology Case Reports, 2023
We encountered a case of multiple system atrophy parkinsonian subtype (MSA-P) with right-dominant parkinsonism in the early stage of the disease. Atrophy of the posterolateral putamen and iron deposition are the neuropathological hallmark of MSA-P ...
Koichiro Mori, MD, Akira Yagishita, MD, Toshio Shimizu, MD, PhD   +2 more
doaj   +1 more source

Pan-American Consortium of Multiple System Atrophy (PANMSA). A Pan-American multicentre cohort study of Multiple System Atrophy

Journal of Parkinson’s Disease, 2014
Background: Multiple system atrophy (MSA) is an adult-onset and rapidly progressive, neurodegenerative condition that presents with autonomic dysfunction, parkinsonism, cerebellar ataxia and corticospinal deficits.
Emilia Gatto, Mayela Rodríguez-Violante, Carlos Cosentino, Pedro Chana-Cuevas, Marcelo Miranda, Ellin Gallin, Jose L. Etcheverry, Yesenia Nuñez, Virginia Parisi, Gabriel Persi, Celeste Vecchi, Ana Sanguinetti, Alejandro Alleva, Juliana Aparcana, Luis Torres, Irene Litvan   +15 more
doaj   +1 more source