Results 21 to 30 of about 21,341,502 (280)

Multiple system atrophy - a clinicopathological update

Free Neuropathology, 2020
Multiple system atrophy (MSA) is a fatal, adult-onset neurodegenerative disorder of uncertain etiology, clinically characterized by various combinations of Levo-dopa-unresponsive parkinsonism, and cerebellar, motor, and autonomic dysfunctions.
Kurt A. Jellinger
doaj   +1 more source

DISTRIBUTION OF NEURONAL CYTOPLASMIC INCLUSIONS IN MULTIPLE SYSTEM ATROPHY [PDF]

, 1995
1995-12-25Neuronal cytoplasmic inclusions (NCls) were demonstrated by means of silver staining (Gallyas staining) in the central nervous systems of 18 deceased patients with multiple system atrophy (MSA) - 6 with olivopontocerebellar atrophy (OPCA), 6 ...
TAKAHASHI, AKIRA, SUGIURA, KENICHI, HASHIZUME, YOSHIO, KUME, AKITO   +3 more
core   +1 more source

Heterogeneity of Multiple System Atrophy: An Update

Biomedicines, 2022
Multiple system atrophy (MSA) is a fatal, rapidly progressing neurodegenerative disease of uncertain etiology, clinically characterized by various combinations of Levodopa unresponsive parkinsonism, cerebellar, autonomic and motor dysfunctions.
Kurt A. Jellinger
doaj   +1 more source

The genetic basis of multiple system atrophy

Journal of Translational Medicine, 2023
Multiple system atrophy (MSA) is a heterogenous, uniformly fatal neurodegenerative ɑ-synucleinopathy. Patients present with varying degrees of dysautonomia, parkinsonism, cerebellar dysfunction, and corticospinal degeneration.
Fan Shuen Tseng, Joel Qi Xuan Foo, Aaron Shengting Mai, Eng-King Tan   +3 more
doaj   +1 more source

Gray matter atrophy rate as a marker of disease progression in AD [PDF]

, 2010
Global gray matter (GM) atrophy rates were quantified from magnetic resonance imaging (MRI) over 6- and 12-month intervals in 37 patients with Alzheimer's disease (AD) and 19 controls using: (1) nonlinear registration and integration of Jacobian values ...
Miller, David H., Nick C. Fox, Kelvin K. Leung, David H. Miller, Anderson, V.M., Anderson, Valerie M, Jonathan W. Bartlett, Leung, Kelvin K, Bartlett, J.W., Bartlett, Jonathan W., Leung, Kelvin K., Fox, Nick C, Schott, Jonathan M, Leung, K.K., Fox, Nick C., Schott, Jonathan M., Valerie M. Anderson, Fox, N.C., Anderson, Valerie M., Schott, J.M., Bartlett, Jonathan W, Jonathan M. Schott, Miller, David H, Miller, D. H., Schott, JM, Fox, NC, Leung, KK, Miller, DH, Anderson, Valerie, Bartlett, JW   +29 more
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Multiple Sistem Atrophy: Sebuah Laporan Kasus

Aksona, 2021
Pendahuluan: Multiple sistem atrophy adalah penyakit degeneratif yang dapat menyebabkan kecacatan bahkan kematian. Sedikit jurnal yang yang membahas tentang diagnosis dan penanganan multiple system atrophy secara menyeluruh.
Edfina Rahmarini, Muhammad Hamdan, Priya Nugraha, Paulus Sugianto, Yudha Haryono   +4 more
doaj   +1 more source

Multiple system atrophy cerebellar variant: pathological implications of the neural connectivity

, 2023
Introducción. La atrofia multisistémica (MSA) es una enfermedad neurodegenerativa progresiva que afecta principal mente la materia blanca (WM, por su sigla en inglés). Este tipo de atrofia se caracteriza por ocasionar inclusiones cito plasmáticas gliales
Sandoval Traslaviña, Karen, Guardias Garzon, Juan Andres, Caceres Urbano, Laura Daniela, Leon Malkun, Luis Alejandro, Huerfano Tamaro, Nataly Andrea, Gutiérrez Huertas, Jessica Liliana   +5 more
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Models of multiple system atrophy [PDF]

Experimental & Molecular Medicine, 2019
AbstractMultiple system atrophy (MSA) is a neurodegenerative disease with diverse clinical manifestations, including parkinsonism, cerebellar syndrome, and autonomic failure. Pathologically, MSA is characterized by glial cytoplasmic inclusions in oligodendrocytes, which contain fibrillary forms of α-synuclein.
Lee, He-Jin, Ricarte, Diadem, Ortiz, Darlene, Lee, Seung-Jae   +3 more
openaire   +2 more sources

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis [PDF]

, 2010
Cerebral atrophy is a correlate of clinical progression in multiple sclerosis (MS). Mitochondria are now established to play a part in the pathogenesis of MS.
Turnbull, Doug M, Kim J. Krishnan, Iryna Ziabreva, Owain Howell, Graham R. Campbell, Don J. Mahad, Reynolds, Richard, Owen Howell, Mahad, Don J, Reeve, Amy K, Amy K. Reeve, Richard Reynolds, Ziabreva, Iryna, Campbell, Graham R, Lassmann, Hans, Doug M. Turnbull, Howell, Owen, Krishnan, Kim J, Hans Lassmann   +18 more
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Multiple system atrophy-cerebellar: A case report and literature review

Radiology Case Reports, 2023
We reported a case of a 48-year-old female patient admitted to the hospital due to balance disorder which progressed rapidly within 1 week. Cerebral magnetic resonance imaging showed significant atrophy and hyperintensities at the middle cerebellar ...
Thi Thuong Doan, MD, Thuy Dung Pham, MD, Duy Duan Nguyen, MD, Dac Hong An Ngo, MD, Trong Binh Le, MD, PhD, Thanh Thao Nguyen, MD, PhD   +5 more
doaj   +1 more source