Results 41 to 50 of about 474,911 (268)

Local farmers' perceptions of ecosystem services and disservices provided by the Black-necked Crane (Grus nigricollis) and their conservation implications

open access: yesGlobal Ecology and Conservation, 2023
Incorporating local farmers' perceptions into conservation management has great significance because they have become the key stakeholders in wildlife conservation, especially that of waterbirds.
Lanyan Zhong   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Rare gene capture in predominantly androgenetic species [PDF]

open access: yesProceedings of the National Academy of Sciences, 2011
The long-term persistence of completely asexual species is unexpected. Although asexuality has short-term evolutionary advantages, a lack of genetic recombination leads to the accumulation over time of deleterious mutations. The loss of individual fitness as a result of accumulated deleterious mutations is expected to lead to reduced ...
Shannon M, Hedtke   +2 more
openaire   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Fatal attraction: rare species in the spotlight [PDF]

open access: yesProceedings of the Royal Society B: Biological Sciences, 2009
The exploitation of rare and endangered species can end in the species's extinction because the increased value people associate with rarity increases the economic incentive to exploit the last individuals, creating a positive feedback loop. This recently proposed concept, called the anthropogenic Allee effect (AAE), relies on the assumption that ...
Angulo, Elena   +3 more
openaire   +3 more sources

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

Two rare Italian Palliduphantes species (Araneae: Linyphiidae)

open access: yesFragmenta entomologica, 2021
Fragmenta Entomologica, Vol. 53 No. 1 (2021)
Alessio Trotta, Robert Bosmans
openaire   +2 more sources

DNA Barcoding Applications in Ants (Hymenoptera: Formicidae)

open access: yesDiversity
Taxonomy is fundamental to all organismic research. Therefore, the integration of molecular and morphological data is increasingly encouraged for more accurate species identification.
Jue Wang   +3 more
doaj   +1 more source

Optimization of Extraction Conditions of Carotenoids from Dunaliella parva by Response Surface Methodology

open access: yesMolecules, 2022
Extraction conditions can exert a remarkable influence on extraction efficiency. The aim of this study was to improve the extraction efficiency of carotenoids from Dunaliella parva (D. parva).
Yujia Li   +3 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

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