Results 91 to 100 of about 199,076 (315)

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

Arthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

Rickettsia sibirica mongolitimonae Infections in Spain and Case Review of the Literature

Emerging Infectious Diseases
Rickettsia sibirica mongolitimonae is an emerging cause of tickborne rickettsiosis. Since the bacterium was first documented as a human pathogen in 1996, a total of 69 patients with this infection have been reported in the literature.
Sonia Santibáñez, José Manuel Ramos-Rincón, Paula Santibáñez, Cristina Cervera-Acedo, Isabel Sanjoaquín, Encarnación Ramírez de Arellano, Sara Guillén, María del Carmen Lozano, Marta Llorente, Mario Puerta-Peña, Elena Aura Bularca, Alejandro González-Praetorius, Isabel Escribano, Lorenzo Sánchez, Valvanera Ibarra, Jorge Alba, Ana M. Palomar, Antonio Beltrán, Aránzazu Portillo, José A. Oteo   +19 more
doaj   +1 more source

Differential Effects of Reward Drive and Rash Impulsivity on the Consumption of a Range of Hedonic Stimuli [PDF]

, 2016
Belinda C. Goodwin, Matthew Browne, Matthew Rockloff, Natalie J. Loxton   +3 more
openalex   +1 more source

Supporting doctors' professional identity development through specialist training

Anatomical Sciences Education, EarlyView.
Abstract Anatomy‐centric specialties such as surgery, radiology, and anatomical pathology (AP) have workforce shortages, with attrition during the training phase proposed as a contributing factor. Current understanding of the reasons behind trainee attrition is limited, and there have been calls to increase the depth and richness of research in this ...
Shemona Y. Rozario, Melanie K. Farlie, Mahbub Sarkar, Michelle D. Lazarus   +3 more
wiley   +1 more source

A 23‐year‐old woman with fever, rash, and arthritis [PDF]

, 2010
Sarah B. Gratton, John B. Imboden
openalex   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

Cystic fibrosis: desensitization in delayed hypersensitivity reactions to elexacaftor/tezacaftor/ivacaftor

Frontiers in Pharmacology
Background: Cystic fibrosis transmembrane conductance regulator modulators are the only available treatment for cystic fibrosis. Although elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) is well-tolerated, rash has been reported as very frequent. In severe
L. Gómez-Ganda, P. Galván-Blasco, P. Galván-Blasco, A. Fernández-Polo, V. Cardona, V. Cardona, B. García-Palop, CJ Parramón-Teixidó, E. Polverino, A. Álvarez-Fernández   +9 more
doaj   +1 more source

Diarrhea, negative t-waves, fever and skin rash, rare manifestation of carbamazepine hypersensitivity: a case report [PDF]

, 2008
Felix Aigner, Wolfgang Aigner, Friedrich Hoppichler, Gerhard Luef, Hugo Bonatti   +4 more
openalex   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Case 2: Rash and allegations of neglect [PDF]

, 2005
Steven Bellemare
openalex   +1 more source