Results 101 to 110 of about 5,283,585 (380)

GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease

, 2022
Jay S. Schneider, Garima Singh, Courtney K. Williams, Vikrant Singh   +3 more
openalex   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Comparative Analysis of Reinforcement Learning Algorithms for Bipedal Robot Locomotion

IEEE Access
In this research, an optimization methodology was introduced for improving bipedal robot locomotion controlled by reinforcement learning (RL) algorithms.
Omur Aydogmus, Musa Yilmaz
doaj   +1 more source

Angiotensin-Converting Enzyme (ACE) 2 Overexpression Ameliorates Glomerular Injury in a Rat Model of Diabetic Nephropathy: A Comparison with ACE Inhibition [PDF]

, 2010
Chun Xi Liu, Qin Hu, Yan Wang, Wei Zhang, Zhi Yong, Jin Feng, Rong Wang, Xu Ping Wang, Bo Dong, Fei Gao, Ming Xiang Zhang, Yun Zhang   +11 more
openalex   +1 more source

The Positive Effects of Poria cocos Extract on Quality of Sleep in Insomnia Rat Models [PDF]

, 2022
Hyeyun Kim, In-June Park, Kyunyong Park, Seohyun Park, Yeong Shik Kim, Byong‐Gon Park   +5 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype [PDF]

, 2016
Hazel Quek, John Luff, KaGeen Cheung, Sergei Kozlov, Magtouf Gatei, C. Soon Lee, Mark C. Bellingham, Peter G. Noakes, Yi Chieh Lim, Nigel L. Barnett, Steve Dingwall, Ernst J. Wolvetang, Tomoji Mashimo, Tara L. Roberts, Martin F. Lavin   +14 more
openalex   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source