Results 101 to 110 of about 3,724,057 (366)

Identification of a Carcinoembryonic Antigen Gene Family in the Rat [PDF]

open access: yes, 1989
The existence of a carcinoembryonic antigen (CEA)-like gene family in rat has been demonstrated through isolation and sequencing of the N- terminal domain exons of presumably five discrete genes (rnCGM1-5).
Barnert, Sabine   +5 more
core  

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

A RATional choice for translational research?

open access: yesDisease Models & Mechanisms, 2016
Future prospects continue to be strong for research using the rat as a model organism. New technology has enabled the proliferation of many new transgenic and knockout rat strains, the genomes of more than 40 rat strains have been sequenced, publications
Tim Aitman   +2 more
doaj   +1 more source

CYP3A Mediated Ketamine Metabolism is Severely Impaired in Liver S9 Fractions from Aging Sprague Dawley Rats [PDF]

open access: yesarXiv, 2015
Ketamine is widely used in veterinary medicine and in medicine. Ketamine is metabolized to its active metabolite norketamine principally by liver CYP3A. Drug metabolism alterations during aging have severe consequences particularly in anesthesiology and very few studies on older animals were conducted for ketamine. The objective of the present study is
arxiv  

Theurapeutic Effectiveness of Rat Bone Marrow Stem Cells in Poly Cystic Ovary Syndrome Mice Model on Folliculogenesis, TGF-β, GDF-9 Expression, and Estrogen, TNF- and Androgen Levels [PDF]

open access: yes, 2016
Objectives: to identify therapeutic effectiveness of Rat Bone Marrow stem cell in PCOS rats model on folliculogenesis, TGF-beta and GDF-9 expression and on estrogen, TNF-a and androgen levels.Material and Methods: this study is a laboratory experimental ...
Santoso, B. (Budi)   +3 more
core  

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

Infinitesimal K-theory [PDF]

open access: yesJ. Reine Angew. Math. 503 (1998), 129-160, 2000
In this paper we study the fiber F of the rational Jones-Goodwillie character $$ F:=\hofiber(ch:K^\rat(A)@>>>HN^\rat(A)) $$ going from K-theory to negative cyclic homology of associative rings. We describe this fiber F in terms of sheaf cohomology. We prove that, for $n\ge 1$, there is an isomorphism: $$ \pi_n(F)\cong H^{-n}_{inf}(A,K^\rat) $$ between ...
arxiv  

Genealogi Ilmu Pemerintahan [PDF]

open access: yes, 2003
ABSTRAK Government as a focus of government studies can be defined as organized and systematic activities, which originated from sovereign and independent entity which has its fundamentals to he identified as a state, which ruled over its citizens and ...
Josef Rat Kaho
core   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

Rat Coronavirus Infection, Lung, Rat [PDF]

open access: yes, 1985
Naturally infected adult rats rarely have grossly observable changes. Experimentally infected 9–10 week old axenic rats develop gross lesions in the lung on postinoculation days 6 and 7, which consist of randomly dispersed red-brown to gray foci, less than 1 mm in diameter (Bhatt and Jacoby 1977). Although rat coronavirus may cause fatal pneumonia in a
openaire   +3 more sources

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