Results 51 to 60 of about 1,677,827 (316)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Standards des sicheren Datenzugangs in den Sozial- und Wirtschaftswissenschaften: Überblick über verschiedene Remote-Access-Verfahren [PDF]
, 2017 Die Forschung in den Sozial- und Wirtschaftswissenschaften ist immer öfter auf einen abgesicherten Zugang zu Forschungsdaten angewiesen, da ansonsten die Anforderungen des Datenschutzes nicht erfüllt werden können.
Goebel, Jan +9 more
core +1 more source
casanchez/rodenticide-rat-infection: Rodenticide and rat infection analysis v1.0.0
, 2021 Code to generate results and figures for Murray & Sánchez. Urban rat exposure to anticoagulant rodenticides and zoonotic infection risk.
Cecilia A. Sanchez
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
SysBioChalmers/Rat-GEM: Rat 1.4.0
, 2023 Main improvements in this PR: Fixes (PR 460): fix: correct MAM03882 annotation, as reported in Mouse-GEM #21 Fixes (PR 429): feat: add Acod1(Irg1) gene and associated reaction, as discussed in Mouse-GEM #20 Features: update ortholog pairs from ...
johan-gson, Hao Wang, Jonathan Robinson
core +1 more source
Molecular Medicine, 2016 We investigated the pathophysiology of diet-induced diabetes in the Cohen diabetic rat (CDs/y) from its induction to its chronic phase, using a multilayered integrated genomic approach.
Yoram Yagil +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
IEEE AccessIncreasing data complexity in clinical decision-making processes hinders physicians’ ability to make rapid and accurate decisions. This study proposes an innovative solution to this problem by designing a multi-layered, adaptive Clinical Decision ...
Cagatay Umut Ogdu +2 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source