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Evaluation of the mechanism of action of albendazole on adult rat lungworm (Angiostrongylus cantonensis)

Experimental Parasitology, 2022
Albendazole is considered the anthelmintic of choice for the management of rat lungworm disease (neuroangiostrongyliasis), due to its broad spectrum of nematocidal activity and its ability to cross the blood-brain barrier. Albendazole binds to β-tubulins, preventing their polymerization into microtubules, thereby corrupting the cascade of cell division
John Jacob   +2 more
exaly   +3 more sources

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