Results 221 to 230 of about 245,926 (298)

A Retrospective Review Exploring the Role of Gender and Frequency of Tonsillectomy, Adenoidectomy, and Tympanostomy in Pediatric Patients With Speech Delay. [PDF]

Cureus
Patel R, Rua S, Patel J, Harvey G, Maddrell R.   +4 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Effects of Very Early versus Early Mobilization and Walking on Functional and Psychosocial Outcomes in Acute Phase After Total Hip Arthroplasty: A Prospective Observational Study. [PDF]

Arthroplast Today
De Leo D, Temporiti F, Della Gatta S, Conti D, Adamo P, Gatti R.   +5 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Analysis of Multi-Domain Factors Influencing Mental Health and Suicide: A Comparative Study of Urban and Rural Areas at City, County, and District Levels in Korea. [PDF]

J Korean Med Sci
Kim C, Kim Y, Lee A, Lee W, Choi Y, Kim H, Lee M, Yang JH.   +7 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Goal Setting According to Level of Mobility Independence in Home-Visit Rehabilitation Using Canadian Occupational Performance Measure. [PDF]

Prog Rehabil Med
Narukawa R, Otaka E, Sato K, Kamiya T, Kawamura S, Iwase T, Kamiya M, Shimotori D, Kagaya H.   +8 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

First Clinical Results of a Multicentric Prospective Study on the Visual Performance of Patients Implanted with a New Trifocal Aspheric Hydrophobic Intraocular Lens. [PDF]

Clin Ophthalmol
Auffarth GU, Kretz FTA, Tañá-Rivero P.
europepmc   +1 more source