Results 91 to 100 of about 6,418,597 (300)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Improved Electrochemical Performance of Lithium-Sulfur Batteries with Boron-Doped Zinc Cobalt Sulfide Catalyst-Modified Separators [PDF]
Iranian Journal of Chemistry & Chemical EngineeringLithium-sulfur (Li-S) batteries possess considerable potential for high theoretical energy density; however, their practical implementation has been impeded by the polysulfide shuttle effect, resulting in inadequate cycling stability.
Binran Cui
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
New Anger Scintillation Cameras with Improved Count Rate Capability
RADIOISOTOPES, 1980 This paper proposes scintillation cameras which can handle input pulse rates beyond 1 Mcps with negligible as spatial resolution and energy resolution at low pulse rates. The cameras are based on the "variable sampling-time technique", in which phototube current pulses are first shortened in width and then selectively integrated by gated integrators ...
TANAKA, Eiichi +2 more
openaire +3 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Sen and the art of educational maintenance: evidencing a capability, as opposed to an effectiveness, approach to schooling [PDF]
, 2012 There are few more widely applied terms in common parlance than ‘capability’. It is used (inaccurately) to represent everything from the aspiration to provide opportunity to notions of innate academic ability, with everything in between claiming ...
Kelly, Anthony
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Future of Capability Management
, 2018 Capability management has been the subject of a lot of research during the past years. Many of the results achieved have been presented in the previous chapters.
Kurt Sandkuhl +5 more
core +1 more source
POINT ESTIMATION OF THE PROCESS CAPABILITY INDEX C(pk) [PDF]
, 1995 In this paper point estimation of the process capability index C(pk) is considered. In order to improve on the natural estimator, a simple alternative estimator is proposed and its mean square error is evaluated ...
Nagata, Yasushi
core +1 more source
FibersContact resistance between the cathode active material (CAM) and the Al current collector can be reduced by applying carbon coatings to the Al current collector surface.
Jaswinder Sharma +7 more
doaj +1 more source