Results 131 to 140 of about 1,348,142 (299)
Frontiers in NeurologyBackgroundThe clinical impact of patient selection using FLAIR vascular hyperintensity (FVH)–diffusion-weighted imaging (DWI) mismatch for endovascular thrombectomy (EVT) in patients who have been symptomatic for over 6 h remains unclear.
Leilei Luo +8 more
doaj +1 more source
Inflation in Developing Countries: Does Central Bank Independence Matter? [PDF]
We analyse whether central bank independence (CBI) affects inflation in developing countries. For this purpose we have constructed a new data set for the turnover rate (TOR) of central bank governors for a very large sample of countries, which also ...
Jakob de Haan, Jan-Egbert Sturm
core
The Prospects of M-Voting Implementation in Nigeria [PDF]
, 2007 Since independence, an average of 50% of registered voters participates in voting [1]. Similarly, an increasing rate of apathy was observed between the electorate and the elect, which was not unconnected with lack of transparency, accountability, and ...
Ayo, C. K., Ekong, U. O.
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Effective monetary policy conservatism: A comparison of 11 OECD countries [PDF]
Modern monetary economists argue that institutional aspects such as central bank independence and central bank conservatism play an important role for the performance of an economy.
Berlemann, Michael, Hilscher, Kai
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Ecos de Economía, 2013 The purpose of this paper is to determine whether professionals in the south of the Aburra Valley save money, and if there is any relationship between their money income and the savings rate.
Elkin Rave Gómez
doaj
Journal of Stroke and Cerebrovascular DiseasesBackground: Both hyperbaric oxygen therapy and Danshen (Salvia miltiorrhiza) injection have shown potential therapeutic effects on ischemic stroke, but the impact of their combination on long-term functional outcomes and recurrence risk has not been ...
Mo Zheng, Yun Xu
doaj +1 more source