Results 81 to 90 of about 1,637,948 (328)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The Virtual Element Method with curved edges

, 2018
In this paper we initiate the investigation of Virtual Elements with curved faces. We consider the case of a fixed curved boundary in two dimensions, as it happens in the approximation of problems posed on a curved domain or with a curved interface ...
da Veiga, L. Beirão, Russo, A., Vacca, G.   +2 more
core   +1 more source

Rates of Best Rational Approximation of Analytic Functions

Journal of Approximation Theory, 2000
Let \(f\) be holomorphic on a compact set \(E\) in the extended complex plane \(\mathbb{C}\). For any nonnegative integer \(n\) let \(\rho_n\) denote the distance of \(f\) from the class \({\mathcal R}_n\) of all rational functions of order at most \(n\), measured with respect to the uniform norm on \(E\). In a previous paper the author [Mat. Sb.
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

RATE OF APPROXIMATION FOR INTEGRATED SZASZ-MIRAKYAN OPERATORS

Demonstratio Mathematica, 2008
AbstractRecently Jain et al. [
Deepak Kumar Dubey, V. K. Jain
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Universal Function Approximation by Deep Neural Nets with Bounded Width and ReLU Activations [PDF]

Mathematics, 2017
This article concerns the expressive power of depth in neural nets with ReLU activations and a bounded width. We are particularly interested in the following questions: What is the minimal width w min ( d ) so that ReLU nets of width w min ( d ) (and ...
Boris Hanin
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Approximation Properties of a Fractional Integral-Type Szász–Kantorovich–Stancu–Schurer Operator via Charlier Polynomials

Mathematics
The goal of this manuscript is to introduce a new Stancu generalization of the modified Szász–Kantorovich operator connecting Riemann–Liouville fractional operators via Charlier polynomials.
Nadeem Rao, Mohammad Farid, Nand Kishor Jha   +2 more
doaj   +1 more source