Results 41 to 50 of about 166,138,308 (237)
Binary Social Mimic Optimization Algorithm With X-Shaped Transfer Function for Feature Selection
IEEE Access, 2020 Definitive optimization algorithms are not able to solve high dimensional optimization problems when the search space grows exponentially with the problem size, and an exhaustive search also becomes impractical. To encounter this problem, researchers use
Kushal Kanti Ghosh +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2020 In this paper, we study the rate in the Smoluchowski–Kramers approximation for the solution of the equation Xt=x+BtH+∫0tb(Xs)ds where {BtH,t∈[0,T]} is a fractional Brownian motion with Hurst parameter H∈(12,1).
Son T.C.
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Rate of convergence of Wong-Zakai approximations for SDEs and SPDEs [PDF]
, 2005 In the work we estimate the rate of convergence of the Wong-Zakai type of approximations for SDEs and SPDEs. Two cases are studied: SDEs in finite dimensional settings and evolution stochastic systems (SDEs in the infinite dimensional case).
Shmatkov, Anton
core
An adaptive finite element approximation of a variational model of brittle fracture [PDF]
, 2010 The energy of the Francfort–Marigo model of brittle fracture can be approximated, in the sense of Gamma-convergence, by the Ambrosio–Tortorelli functional.
Christoph Ortner +8 more
core +1 more source
IEEE Access, 2018 In a typical downlink massive multiple-input and multiple-output (massive MIMO) system, the available degree of freedom (DoF) and multiplexing gain improve the channel rate.
James Kweku Nkrumah Nyarko +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source