Results 51 to 60 of about 166,138,308 (237)
On the improved convergence of lifted distributional Gauss curvature from Regge elements
Although Regge finite element functions are not continuous, useful generalizations of nonlinear derivatives like the curvature, can be defined using them.
Jay Gopalakrishnan +3 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A chemical-reaction-optimization-based neuro-fuzzy hybrid network for stock closing price prediction
Accurate prediction of stock market behavior is a challenging issue for financial forecasting. Artificial neural networks, such as multilayer perceptron have been established as better approximation and classification models for this domain.
Sarat Chandra Nayak, Bijan Bihari Misra
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Rate of convergence in Trotter's approximation theorem
We give a quantitative estimate of the convergence in Trotter's approximation theorem on the convergence of iterates of linear operators to an assigned semigroup.
TACELLI, CRISTIAN +3 more
core +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Approximation Error Bounds via Rademacher's Complexity [PDF]
Approximation properties of some connectionistic models, commonly used to construct approximation schemes for optimization problems with multivariable functions as admissible solutions, are investigated.
Gnecco, Giorgio, Sanguineti, Marcello
core
Modified Fourier expansions: theory, construction and applications [PDF]
Modified Fourier expansions present an alternative to more standard algorithms for the approximation of nonperiodic functions in bounded domains. This thesis addresses the theory of such expansions, their effective construction and computation, and ...
core +2 more sources
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source

