Results 91 to 100 of about 167,647,873 (306)
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Report from the Governor's Task Force on Cultural Development
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from coverMode of access: Internet from the Oregon ...
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How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Background: Temporomandibular disorders (TMDs) are associated with altered masticatory muscle function and pain. Although electromyographic parameters have been extensively studied, the rate of force development (RFD) remains an underexplored biomarker ...
Bianca Rossi Botim +10 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Sarah K Perry, Harsh H Buddhadev, Lorraine R Brilla, David N Suprak Department of Health and Human Development, Western Washington University, Bellingham, WA, USACorrespondence: Harsh H BuddhadevDepartment of Health and Human Development, Western ...
Perry SK +3 more
doaj
Background and study aims The impairment of the knee muscles brought on by knee osteoarthritis alters motor function, lowers levels of physical activity, and raises the risk of falling.
Mennatallah Ali Ibrahim Aldesouky Elshafey +3 more
doaj +1 more source
Kansas aquaculture : strategy for development : a report of the Kansas Aquaculture Task Force.
Cover title.; "July, 1991."; "In early 1990, the Governor's Office assigned to the Board of Agriculture the responsibility of formulating the Kansas Aquaculture Task Force and development of a state aquaculture plan.
Kansas Aquaculture Task Force.
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2018 Partnership Report: A Decade of Partnership
In 2018, partnerships were once again at the center of the Inter-American Development Bank Group’s (IDB Group) efforts to improve lives in Latin America and the Caribbean.
Inter-American Development Bank
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Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source

