Results 121 to 130 of about 915,295 (349)

The rate of penetration of liquid into tablets.

Chemical and Pharmaceutical Bulletin, 1981
A direct measuring method for the liquid penetration rate into tablets was devised and compared with the usual powder method. The effect of the diameter and shape of tablets on the penetration rate was examined by using a two-dimensional model and confirmed to be negligible in practice.
E, Fukuoka, S, Kimura, M, Yamazaki
openaire   +3 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Penetration rates of new pharmaceutical products in Europe: A comparative study of several classes recently launched in type-2 diabetes

, 2021
Claude Le Pen, B. Bauduceau, X. Ansolabehere, A. Troubat, Sébastien Bineau, Mahaut Ripert, S. Dejager   +6 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Solvent Penetration Rate in Tablet Measurement Using Video Image Processing [PDF]

, 2012
Daniel Braido, Yuriy Gulak, Alberto M. Cuitiño   +2 more
openalex   +1 more source

Muon-spin-relaxation study of the magnetic penetration depth in MgB2

, 2001
The magnetic vortex lattice (VL) of polycrystalline MgB2 has been investigated by transverse-field muon-spin-relaxation (TF-MuSR). The evolution of TF-MuSR depolarization rate, sigma, that is proportional to the second moment of the field distribution of
A. Amato, A.M. Mulders, A.Y. Liu, B. Mühlschlegel, B. Pümpin, C. Bernhard, C. Panagopoulos, Ch. Niedermayer, Ch. Niedermayer, Ch. Walti, D. Harshman, D.G. Hinks, E.H. Brandt, F. Bouquet, G. Karapetrov, H. Kotegawa, J. Kortus, J. Nagamatsu, K. Ahn, M. Xu, O.F. de Lima, P.J. Hirschfeld, R. K. Kremer, R. Osborn, R.S. Hayano, S. Haas, S. Lee, S. Patnaik, S.L. Bud‘ko, T. Holden, T. Takahashi, T. Yildirim, W. Bardford, W.N. Hardy, X.K. Chen, Y. Wang   +35 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Insight into drilling performance parameters for in-situ detection of lithological transition

Scientific Reports
In order to examine the rock dependence on drilling performance parameters, such as torque and rate of penetration (ROP), we conducted laboratory drilling experiments using mafic and ultramafic rocks from the Oman ophiolite and the Horoman Complex ...
Kazumasa Tanimoto, Yohei Hamada, Ikuo Katayama   +2 more
doaj   +1 more source