Results 61 to 70 of about 912,950 (301)

Diffusion of mobile phones in Portugal: unexpected success? [PDF]

, 2006
This paper begins with a somewhat paradoxical situation: Portugal is one of the less innovative countries within the European Union by most innovation indicators but, simultaneously, it is a leading country in the diffusion of mobile phones.
Carvalho, Adão
core  

Stability Analysis of a Hybrid Cellular Automaton Model of Cell Colony Growth

, 2007
Cell colonies of bacteria, tumour cells and fungi, under nutrient limited growth conditions, exhibit complex branched growth patterns. In order to investigate this phenomenon we present a simple hybrid cellular automaton model of cell colony growth.
A. R. A. Anderson, B. Mandelbrot, C. M. Regalado, D. Thompson, H. Frieboes, M. Vilela, P. Gerlee   +6 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Exploration of Training Strategies for a Quantile Regression Deep Neural Network for the Prediction of the Rate of Penetration in a Multi-Lateral Well

Energies
In recent years, rate of penetration (ROP) prediction using machine learning has attracted considerable interest. However, few studies have addressed ROP prediction uncertainty and its relation to training data and model inputs.
Adrian Ambrus, Felix James Pacis, Sergey Alyaev, Rasool Khosravanian, Tron Golder Kristiansen   +4 more
doaj   +1 more source

Single vortex fluctuations in a superconducting chip as generating dephasing and spin flips in cold atom traps

, 2012
We study trapping of a cold atom by a single vortex line in an extreme type II superconducting chip, allowing for pinning and friction. We evaluate the atom's spin flip rate and its dephasing due to the vortex fluctuations in equilibrium and find that ...
Amir Fruchtman, Baruch Horovitz, Campbell A. M., Campbell A. M., Kasch B., Müller T., Nogues G., Tinkham M.   +7 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

PDC Bit Optimization and Application in Panyu Oilfield of the South China Sea

Shiyou jixie, 2016
Panyu Oilfield of the South China Sea is subject to several technical problems.For example, soft and hard formations are repeatedly staggered to possibly damage drill bits and tools; plastic soft clay is prone to bit balling; high requirements are raised
Tian Zhixin, Liu Jun
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source