Results 61 to 70 of about 166,367,160 (262)
ClinicoEconomics and Outcomes Research, 2021 Tsugumi Matsumoto,1,2 Takanori Tsuchiya,3 Takahiro Hirano,4 Thomas Laurent,4 Kazuhisa Matsunaga,1 Jiro Takata1 1Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan; 2Inflammation and Immunology Therapeutic Area Medical Affairs, Pfizer ...
Matsumoto T +5 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Effect of properties of materials on penetration
, 2001 The effect of physico-mechanical properties of different penetrator material and various target materials on penetration under different velocity range (from 780 m/s to 8 km/s) was studied. Many interesting phenomena were observed. A subject of efficient
Gao, J (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100080, Peoples R China. +1 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Penetration depth measurements of organic superconductors [PDF]
, 2010 The temperature dependence of the magnetic penetration depth (λ) has been measured in single crystals of fully deuterated κ-(ET)2Cu[N(CN)2]Br. This material separates into superconducting (SC) and antiferromagnetic (AFI) phases.
Olheiser, Tyson A.
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Rate effect of piezocone testing in two soft clays [PDF]
, 2018 The Onsøy and Sarapuí II soft clays have been studied for a number of years. In particular, piezocone tests with different rates have been conducted at both sites. Since the plasticity index and the coefficient of consolidation—which play important roles
Danziger, Fernando +4 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source