Results 71 to 80 of about 915,295 (349)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Bayesian prediction of TBM penetration rate in rock mass
Engineering Geology, 2017 Abstract One of the essential tasks in the excavation of tunnels with TBM is the reliable estimation of its performance needed for the planning, cost control and other decision making on the feasibility of the tunneling project. The current study aims at predicting the rate of penetration (RoP) of TBM on the basis of the rock mass parameters ...
Adoko, Amoussou Coffi +2 more
openaire +2 more sources
'Market penetration and pay-back period analysis of a solar photovoltaic system under Indian conditions' [PDF]
The use of pay-back period analysis for economic evaluation of solar photovoltaic (PV) system reinforces the importance of the duration of the system.
Mohan Lal Kolhe
core
, 2012 We study trapping of a cold atom by a single vortex line in an extreme type II superconducting chip, allowing for pinning and friction. We evaluate the atom's spin flip rate and its dephasing due to the vortex fluctuations in equilibrium and find that ...
Amir Fruchtman +7 more
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Thermally Assisted Penetration and Exclusion of Single Vortex in Mesoscopic Superconductors
, 2012 A single vortex overcoming the surface barrier in a mesoscopic superconductor with lateral dimensions of several coherence lengths and thickness of several nanometers provides an ideal platform to study thermal activation of a single vortex.
B. Petukhov +6 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
On the state of low luminous accreting neutron stars
, 2001 Observational appearance of a neutron star in the subsonic propeller state which is a companion of a wind-fed mass-exchange close binary system is discussed.
Arons +18 more
core +1 more source