Results 281 to 290 of about 13,243,531 (353)

Effectiveness of Neck Lymph Node Dissection for Breast Cancer Patients with Isolated Supraclavicular Nodal Recurrence. [PDF]

Cancer Manag Res
Isozaki H, Yamamoto Y, Murakami S, Matsumoto S, Takama T, Isozaki Y.   +5 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Evolving patterns of bladder cancer mortality in US adults: a two-decade analysis reveals persistent disparities despite overall progress (1999-2020). [PDF]

Front Oncol
Sun L, Liu C, Yuan L.
europepmc   +1 more source

Regional mortality disparities in Central and Eastern Europe 2000-22. [PDF]

J Public Health (Oxf)
Hrzic R, Grigoriev P.
europepmc   +1 more source

The Impact of Cleavage and Blastocyst Stage Sequential Transfer on Clinical Pregnancy Outcomes of Frozen Embryo Transfer in Patients with Multiple Transplant Failures: A Retrospective Cohort Study. [PDF]

Int J Womens Health
Huang C, Liu J, Shen X, Mei J, Jiang Y, Zhang H, Kong N.   +6 more
europepmc   +1 more source

Changes in Fertility Trends and Women's Fertility Desires in the Wake of the Homicide Surge in Mexico. [PDF]

Popul Res Policy Rev
Floridi G, Gargiulo M, Aburto JM.
europepmc   +1 more source

Assessing the burden of HPV-associated cancers in Brazil: Hospitalization and mortality trends from 2011 to 2019. [PDF]

Hum Vaccin Immunother
Parellada CI, Bierrenbach AL, Bittencourt Campaner A, Gonçalves Queijo R, Rocha Sarmento TT, Orengo JC.   +5 more
europepmc   +1 more source

The 30-year evolution of motor vehicle road injuries: Can the future come from the shadows? [PDF]

PLoS One
Zhao S, Lan Z, Lin J, Kan S, Jiao Y, Chen L, Du Y.   +6 more
europepmc   +1 more source