Results 21 to 30 of about 157,001 (214)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender +17 more
wiley +1 more source
Caputo-Fabrizio approach to numerical fractional derivatives
Bibechana, 2023 Fractional calculus is an essential tool in every area of science today. This work gives the quadratic interpolation-based L1-2 formula for the Caputo-Fabrizio derivative, a numerical technique for approximating the fractional derivative.
Shankar Pariyar, Jeevan Kafle
doaj +3 more sources
On the convergence rates of Gladyshev’s Hurst index estimator
Nonlinear Analysis, 2010 This paper presents the convergence rates for a modified Gladyshev’s estimator of the Hurst index of the fractional Brownian motion.
K. Kubilius, D. Melichov
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Nonparametric Pointwise Estimation for a Regression Model with Multiplicative Noise
Journal of Function Spaces, 2021 In this paper, we consider a general nonparametric regression estimation model with the feature of having multiplicative noise. We propose a linear estimator and nonlinear estimator by wavelet method.
Jia Chen, Junke Kou
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Convergence Rates of Gradient Methods for Convex Optimization in the Space of Measures
Open Journal of Mathematical Optimization, 2023 We study the convergence rate of Bregman gradient methods for convex optimization in the space of measures on a $d$-dimensional manifold. Under basic regularity assumptions, we show that the suboptimality gap at iteration $k$ is in $O(\log (k)k^{-1 ...
Chizat, Lénaïc
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Convergence rates of wavelet density estimation for negatively dependent sample
Journal of Inequalities and Applications, 2019 In this paper, linear and nonlinear wavelet estimators are defined for a density in a Besov space based on a negatively dependent random sample, and their upper bounds on Lp $L^{p}$ ( 1 ...
Junlian Xu
doaj +1 more source