Results 51 to 60 of about 157,001 (214)
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Strong Uniform Convergence Rates of Wavelet Density Estimators with Size-Biased Data
Journal of Function Spaces, 2019 This paper considers the strong uniform convergence of multivariate density estimators in Besov space Bp,qs(Rd) based on size-biased data. We provide convergence rates of wavelet estimators when the parametric μ is known or unknown, respectively.
Huijun Guo, Junke Kou
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Mathematics, 2019 In this paper, we consider the initial value problem for the linearized compressible Navier–Stokes–Korteweg system. Asymptotic profiles and convergence rates are established by Fourier splitting frequency technique.
Yinxia Wang
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Rates of convergence for regression with the graph poly-Laplacian. [PDF]
Sampl Theory Signal Process Data Anal, 2023 Trillos NG, Murray R, Thorpe M.
europepmc +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Stability of strong detonation waves and rates of convergence
Electronic Journal of Differential Equations, 1998 In this article, we prove stability of strong detonation waves and find their rate of convergence for a combustion model. Our results read as follows: I) There exists a global solution that converges exponentially in time to a strong detonation wave ...
Tong Li
doaj
International Journal of Mathematics and Mathematical Sciences, 2009 Let {X,Xn¯;n¯∈Z+d} be a sequence of i.i.d. real-valued random variables, and Sn¯=∑k¯≤n¯Xk¯, n¯∈Z+d. Convergence rates of moderate deviations are derived; that is, the rates of convergence to zero of certain tail probabilities of the partial sums are ...
Dianliang Deng
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