Results 31 to 40 of about 406,466 (263)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The 2020 COVID-19 Financial Crisis Impact on the European Stock Markets and Economies. A Preliminary Analysis

Folia Oeconomica Stetinensia
In mid-April 2020, the global financial markets plunged into financial crisis from the unprecedented worldwide lockdowns for an extended period.
Foo Jennifer, Witkowska Dorota
doaj   +1 more source

PROFITABILITY OF THE COMPANY EXPRESSED UNDER RENTABILITY RATES [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2018
The goal of any firm is to make enough profit to properly capitalize its capital, maintain its technical and economic potential, and ensure rational expansion taking into account market developments and short-term trends.
CĂRUNTU GENU ALEXANDRU, ECOBICI MIHAELA LOREDANA   +1 more
doaj  

High return to sports rates after operative treatment of patella fractures

European Journal of Medical Research, 2023
Background Patella fractures are relatively rare fractures and only little is known about the postoperative return to sports after patella fractures. Methods This retrospective study presents information on functional outcome after operative treatment of
Sebastian Pesch, Frederik Greve, Michael Zyskowski, Michael Müller, Moritz Crönlein, Peter Biberthaler, Chlodwig Kirchhoff, Markus Wurm   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Return to Play Rates of Young Athletes After Patellofemoral Instability Treatment

Orthopaedic Journal of Sports Medicine, 2022
Background: Following non-operative or operative treatment, many young patients with patellofemoral instability (PFI) desire to return to sport. The rate of return to play in young athletes following PFI treatment is not well known.
Madison Brenner BASc, Savannah Cooper MS, Benjamin L. Johnson MPAS, P.A.-C., Charles W. Wyatt MS, CPNP, Philip L. Wilson MD, Henry B. Ellis MD   +5 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Private Rate of Return on Human Capital Investment in the Czech Republic: Differences by Study Fields [PDF]

Statistika: Statistics and Economy Journal, 2012
The paper is focused on approaches to the measurement of the returns of private investments on human capital in the Czech Republic. In the last ten years, there is observed a significant increase in number ofstudents at Higher Education Institutions ...
Savina Finardi, Jakub Fischer, Petr Mazouch   +2 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source