Results 41 to 50 of about 406,466 (263)
The ANNALS of the American Academy of Political and Social Science, 1914 n ...
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
REMARKS ON THE ECONOMIC-FINANCIAL RATE OF RETURN FOR A LARGE ECOLOGICAL FARM IN SOUTHERN ROMANIA [PDF]
Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2014 Ecological agriculture is a developing sector in Romania, the farms’ profitability depending directly on their physical and economic size. Large ecological farms are fewer in this sector, but due to their size they succeed in dealing better with high ...
Aurelia BĂLAN +3 more
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Heterogeneity in schooling rates of return [PDF]
Economics of Education Review, 2011 Abstract This paper relaxes the assumption of homogeneous rates of return to schooling by employing nonparametric kernel regression. This approach allows us to examine the differences in rates of return to education both across and within groups. Similar to previous studies we find that on average blacks have higher returns to education than whites ...
Henderson, Daniel J. +2 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Stock market return and merger and acquisition activity in Poland
Research Papers in Economics and FinanceThis article explores mergers and acquisitions trends in the Polish market in a period between 2019 and 2022, focusing on transactions exceeding one million dollars and their correlation with sector-specific stock market returns.
Eliasz Czajkowski, Mateusz Mikutowski
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Determinan Return Saham Industri Otomotif dan Komponen yang Terdaftar di BEI
Trikonomika, 2015 This study is aimed at determining the effect of Return on Equity (ROE), Debt to Equity Ratio (DER), Net Profit Margin (NPM), inflation, exchange rates, and interest rates on stock return of Automotive Industry and its Components.
Jaja Suteja, Patrisius Seran
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
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