A divergence diagnostic for monitoring the composition of default in rating-migration matrices. [PDF]
MethodsXTolikas K.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
More analysts, better ratings: Do rating agencies invest enough in less developed countries? [PDF]
Rating agencies' track record is good in developed countries but poor in emerging economies. Why? Given the almost-monopolistic structure of the industry, we conjecture that agencies might underinvest in information gathering.
Giovanni Ferri
core
Validation of the Quick Dementia Rating System (QDRS): diagnostic properties and cutoff values. [PDF]
Dement NeuropsycholSenger JE +13 more
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
CREDIT RISK ASSESSMENT BY RATING AGENCIES: STANDARDIZATION VERSUS SUBJECTIVITY [PDF]
The development of the international financial market, the globalization of the financial resources and the increase of the world economic insecurity have been accompanied by the exponential rising of the corporate rating after 1980.
Monica Dudian
core
Powering Neurology Drug Development Trials to Reduce False Negative Results. [PDF]
Clin Transl SciMori H +3 more
europepmc +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Do market-based indicators anticipate rating agencies? Evidence for international banks [PDF]
This paper analyzes the ability of credit default swap spreads, bond spreads and stock prices to anticipate the decisions of the main rating agencies, for the largest international banks.
Antonio Di Cesare
core
Regional variations in inpatient satisfaction: a nationwide analysis of ministry of health hospitals in Saudi Arabia. [PDF]
Front Public HealthDaeab EK +10 more
europepmc +1 more source