Results 251 to 260 of about 2,723,312 (345)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Adjustment of Assessors' First Impressions Differs by Student Ethnicity. [PDF]

Perspect Med Educ
Steinmann JJ, Otto I, Born MP, Derous E, Woltman AM, van den Broek WW, Stegers-Jager KM.   +6 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Correction to 'A Feasibility Study Assessing a Novel Ambulatory Monitoring System in General Ward Areas: Pilot Study'. [PDF]

Nurs Open
europepmc   +1 more source

Translation and Validation of the User Version of the Mobile Application Rating Scale Into the Polish Language: Cross-Sectional Methodological Study. [PDF]

JMIR Form Res
Glinkowski WM, Cedro T, Nowicka J, Doniec R, Michalak B, Glinkowska B, Stoyanov S.   +6 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Editorial Comment on Efficacy and Safety of Clomiphene Citrate for Late-Onset Hypogonadism as Evaluated by Aging Male Symptom Rating Scale Over 1 Year. [PDF]

Int J Urol
Fukuhara S.
europepmc   +1 more source

Novel way of displaying Delphi responses when collecting through the REDCap data collection system. [PDF]

Trials
Barber VS, Calvert C, Appelbe DE.
europepmc   +1 more source

Serum levels of CaMKII in patients with hyperventilation syndrome and its correlation with anxiety and depression. [PDF]

Medicine (Baltimore)
Luo L, Mao X, Fu W, Song X, Zhou L.
europepmc   +1 more source

Readability Analysis of Commonly Cited Patient-Reported Outcome Measures in the Orthopaedic Joint Literature. [PDF]

Arthroplast Today
Uppal H, Garcia D, Rezzadeh K, Sahai N, McGinniss A, Emami A, Rifai A.   +6 more
europepmc   +1 more source