Results 161 to 170 of about 489,800 (291)

When Agency Fails: An Analysis of the Association Between Hospital Agency Staffing and Quality Outcomes

Risk Management and Healthcare Policy
Bradley Beauvais, Rohit Pradhan, Zo Ramamonjiarivelo, Michael Mileski, Ramalingam Shanmugam School of Health Administration, Texas State University, San Marcos, TX, USACorrespondence: Rohit Pradhan, Email pradhan@txstate.eduIntroduction: Staffing is ...
Beauvais B, Pradhan R, Ramamonjiarivelo Z, Mileski M, Shanmugam R   +4 more
doaj  

Stage 1 registered report examining agency and outcome valence on inter-brain synchrony during dyadic moral judgments. [PDF]

Front Psychol
Hinvest N, Taylor N.
europepmc   +1 more source

Moody’s credit ratings and the stock market performance of Portuguese rated firms [PDF]

Never has the issue of sovereign credit ratings attracted such an interest by policy and opinion makers, bankers and journalists, or even the public opinion, as witnessed in the last couple of years.
Pacheco, Luis
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

A full belly counsels well: More stabilisation with more responsibility. [PDF]

PLoS One
Sheng X.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Assessing Overall Survival Benefits in Advanced Cancers: The Role of External Comparator Cohort Studies with Real-World Data. [PDF]

Clin Pharmacol Ther
Pignatti F, El-Galaly TC, Kaiser M, Porkka K, Doeswijk R, Mol P, Rivera DR, Lerro CC, Rohr UP, Verpillat P, Valachis A, Trapani D, Di Maio M, Latino N, Cordoba R, Cherny N, Koopman M, Martins-Branco D, Pentheroudakis G, Postmus D.   +19 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Florzolotau (18F) retention is linked to neuropsychological performance in tauopathy. [PDF]

Alzheimers Dement
Shimizu A, Iwabuchi Y, Bun S, Watanabe M, Kubota M, Shimohama S, Tezuka T, Takahata K, Tabuchi H, Seki M, Momota Y, Yamamoto Y, Shikimoto R, Mimura Y, Kurose S, Sakurai R, Takayama T, Hoshino Y, Hoshino T, Suzuki N, Morimoto A, Osumi A, Mimura M, Jinzaki M, Ito D.   +24 more
europepmc   +1 more source