Results 111 to 120 of about 327,754 (303)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Hydrodynamic Modeling for Flow and Velocity Estimation from an Arduino Ultrasonic Sensor
HydrologyFlow is a crucial variable in water resources, although its determination is challenging. Rating curves are standard but have conceptual limitations, leading to significantly high uncertainties.
Tatiane Souza Rodrigues Pereira +4 more
doaj +1 more source
Agritech, 2014 Prolonged soil erosion and sedimentation have negative effect on land quality showing by decreasing land productivity, in addition, sedimentation process may cause decreasing function of hydrologic infrastructures.
Nining Wahyuningrum +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Assessment of Estimation Methods ForStage-Discharge Rating Curve in Rippled Bed Rivers
مجله آب و خاک, 2016 Introduction: Interactionbetweenwater flow characteristics andthe bed erodibilityplays an important role in sediment transport process. In order to reach stability, rivers with deposition or bottom erosion make a different bed form in the riverbed.
P. Maleki +3 more
doaj +1 more source
Monitoring and controlling bank risk: does risky debt serve any purpose? [PDF]
To examine whether mandating banks to issue subordinated debt would enhance market monitoring and control risk-taking, the authors extract the credit-spread curve for each banking firm in their sample.
C. N. V. Krishnan +2 more
core
Private Health Insurance Market Reforms in the Affordable Care Act (ACA) [PDF]
, 2014 [Excerpt] This report provides background information about the private health insurance market, including market segments and regulation. It then describes each ACA market reform.
Fernandez, Bernadette, Mach, Annie L
core +4 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
River system sediment rating curve parameter estimation via integrated models
International Journal of Sediment ResearchContinuous water and sediment flow monitoring across river cross sections is essential for the management of flood- and sediment-related problems in watersheds.
Tushar Khankhoje +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source