Results 131 to 140 of about 452,911 (267)

Selection of a Rating Scale in Receiver Operating Characteristic Studies: Some Remaining Issues

, 2008
Howard E. Rockette, David Gur
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Validation of the Norwegian version of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale. [PDF]

Clin Park Relat Disord
Alves G, Sørenes YS, Frantzen VH, Gjerstad MD, Bjørnestad AL, Maple-Grødem J, Forsaa EB, Hiorth YH, Herlofson K, Benjaminsen E, Bjørnarå KA, Dietrichs E, Balestrino R, Gasca-Salas C, Lin CR, Sanchez-Ferro A, Tosin MHS, Mestre TA, Kurtis MM, Martinez-Martin P, Luo S, Yu L, Stebbins GT, Goetz CG, MDS COA Translation Steering Committee.   +24 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Neural and biomarker correlates of the Parkinson's Disease-Cognitive Rating Scale in Huntington's disease. [PDF]

Neuroimage Rep
Martinez-Horta S, Puig-Davi A, Sampedro F, Pérez-Pérez J, Franch-Martí C, Olmedo-Saura G, Rivas-Asensio E, Vazquez-Oliver A, Pérez-Carasol L, Horta-Barba A, Pagonabarraga J, Kulisevsky J.   +11 more
europepmc   +1 more source

Factor Analysis and Validity of the Conners Parent and Teacher Rating Scales in Childhood Cancer Survivors [PDF]

, 2005
Susan Helton, Robert F. Corwyn, Melanie J. Bonner, Ronald T. Brown, Raymond K. Mulhern   +4 more
openalex   +1 more source

Cross-Cultural Adaptation and Psychometric Properties of the Greek Vineland Adaptive Behavior Scales, Second Edition: Parent/Caregiver Rating Form (VABS II-Gr)

, 2022
Aikaterini Katsiana, Anastassios Stalikas, Panagiotis Kokkaris, Michalis Galanakis, Konstantinos Georgiou, Νικόλαος Στριμπάκος   +5 more
openalex   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

ERKEN ÇOCUKLUK DÖNEMİNDE OKUMA YAZMAYA YÖNELİK MOTOR BECERİLERİN DEĞERLENDİRİLMESİ: MOTOR SKİLLS RATİNG SCALE TÜRKÇE’ YE UYARLAMA ÇALIŞMASI

, 2022
Hatice Gözde ERTÜRK KARA, Başak FİLİKCİ   +1 more
openalex   +2 more sources