Results 81 to 90 of about 1,790,394 (354)

Outcome Measures in Clinical Trials of Patients With Myasthenia Gravis

open access: yesFrontiers in Neurology, 2020
Myasthenia gravis (MG) is a heterogeneous disorder whose clinical presentation ranges from mild ocular deficits to severe widespread weakness. This variance poses a challenge when quantifying clinical deficits.
Jan Lykke Scheel Thomsen   +1 more
doaj   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

RatingScaleReduction package: stepwise rating scale item reduction without predictability loss [PDF]

open access: yesarXiv, 2017
This study presents an innovative method for reducing the number of rating scale items without predictability loss. The "area under the re- ceiver operator curve method" (AUC ROC) is used to implement in the RatingScaleReduction package posted on CRAN.
arxiv  

International versions of the Menopause Rating Scale (MRS)

open access: yesHealth and Quality of Life Outcomes, 2003
Background Symptom scales for aging women have clinically been used for years and the interest in measuring health-related quality of life (HRQoL) has increased in recent years.
Schneider Hermann PG   +2 more
doaj   +1 more source

Frontotemporal Dementia Rating Scale (FTD-FRS): Linguistic and Cultural Adaptation in Russia

open access: yesАнналы клинической и экспериментальной неврологии, 2020
Introduction. Frontotemporal dementia (FTD) is a neurodegenerative disease and is the second most frequent cause of early-onset dementia (before 65 years).
Yuliya A. Shpilyukova   +12 more
doaj   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Rate Dependence and Role of Disorder in Linearly Sheared Two-Dimensional Foams [PDF]

open access: yes, 2007
The shear flow of two dimensional foams is probed as a function of shear rate and disorder. Disordered foams exhibit strongly rate dependent velocity profiles, whereas ordered foams show rate independence. Both behaviors are captured quantitatively in a simple model based on the balance of the time-averaged drag forces in the foam, which are found to ...
arxiv   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

Subjective rating scales as a workload [PDF]

open access: yes, 1981
A multidimensional bipolar-adjective rating scale is employed as a subjective measure of operator workload in the performance of a one-axis tracking task.
Bird, K. L.
core   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

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