Results 91 to 100 of about 28,531,139 (282)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Companies operating in the energy sector are under pressure to boost the level of green energy production. The use of renewable energy sources will have a positive impact on the environment, but the basic question is whether power plants that produce ...
Sebastian Klaudiusz Tomczak
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Digit ratio (2D:4D) and male facial attractiveness: New data and a meta-analysis [PDF]
Digit ratio (2D:4D) appears to correlate negatively with prenatal testosterone (T) effects in humans. As T probably increases facial masculinity, which in turn might be positively related to male facial attractiveness, a number of studies have looked ...
Honekopp, Johannes, Johannes Hönekopp
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Estimating adjusted prevalence ratio in clustered cross-sectional epidemiological data. [PDF]
BACKGROUND: Many epidemiologic studies report the odds ratio as a measure of association for cross-sectional studies with common outcomes. In such cases, the prevalence ratios may not be inferred from the estimated odds ratios.
Cooper Philip J +29 more
core +2 more sources
Investment opportunities evaluation: A comparative analysis and the multi-criteria ranking of top-listed companies [PDF]
Investors are faced with the challenge of identifying the most promising companies for their potential investment in the stock market. This research study aims to propose a systematic approach to the selection of top-listed companies for investment ...
Tadija Đukić +2 more
doaj +1 more source
Inventories are rough materials, work-in-process items and completely finished product that are seen as the section of business' points of interest that are arranged or will be readied accessible to be obtained. Itemizing a sensible stock model is one of the genuine stresses for an industry.
openaire +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Poland occupies a high position in both global and European fruit and vegetable production. The large number of small-sized farms has been one of the problems of Polish agriculture for years.National and EU financial help has increased interest in ...
Dawid Olewnicki +2 more
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