Results 101 to 110 of about 28,531,139 (282)
Assessment of profitability indicators of insurance companies in Serbia [PDF]
The insurance sector plays an important role for households and companies, as well as the national economy as a whole. In order to determine the growth opportunities of the insurance sector and its contribution to the development of the national economy,
Aničić Anđelka +3 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
On reducing the cut ratio to the multicut problem
We compare two multicommodity flow problems, the maximum sum of flow, and the maximum concurrent flow. We show that, for a given graph and a given set of k commodities with specified demands, if the minimum capacity of a multicut is approximated by the ...
Ratio To
core
Comparison of Tooth Size Discrepancy of Three Main Ethnics in Malaysia with Bolton's Ratio [PDF]
The objective of this study was to investigate the applicability of Bolton's ratios in orthodontic population of Malaysian main ethnics; Malay, Chinese and Indians.
Othman, S. A., Abd Rahman, A. N. A.
core +1 more source
Methodology of complex analysis of tangible long-term assets
Long-term tangible assets are used by all companies regardless of their size and activity profile. Long-term tangible assets are very significant for companies’ financial results, thus, it is important to perform a detailed analysis of these assets.
Jonas Mackevičius
doaj
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

