Results 131 to 140 of about 8,071,777 (301)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Considerations in the design of tip-coupled air-transport systems [PDF]
It is shown that the lift-drag ratio of tip-coupled systems can be expressed as a simple multiple of the lift-drag ratio of the isolated units comprising the system.
Heyson, H. H.
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Global Stability and Bifurcations of a Diffusive Ratio-Dependent Holling-Tanner System
Abstract and Applied Analysis, 2013 The dynamics of a diffusive ratio-dependent Holling-Tanner predator-prey system subject to Neumann boundary conditions are considered. By choosing the ratio of intrinsic growth rates of predators to preys as a bifurcation parameter, the existence and ...
Wenjie Zuo
doaj +1 more source
Fractional robust control of ligthly damped systems [PDF]
, 2006 The article proposes a method to design a robust controller ensuring the damping ratio of a closed-loop control. The method uses a contour para-meterized by the damping ratio in the Nichols plane and the complex non-integer (or fractional)differentiation
Janat, Yaman +3 more
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Extending Batch Extractive Distillation Thermodynamic Feasibility Insights to Continuous for Class 1.0-2 Case A [PDF]
, 2011 The feasibility of batch and continuous extractive distillation analysis for the separation azeotropic mixtures is addressed. Based on batch feasibility knowledge, batch and continuous separation feasibility is studied under reflux ratio and entrainer ...
Benyounes, Hassiba +2 more
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source