Results 131 to 140 of about 3,665,294 (312)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Controlling Peak-to-Average Power Ratio in Orthogonal Frequency Division Multiplexing System

open access: yesJournal of Engineering and Sustainable Development, 2013
A major drawback of Orthogonal Frequency Division Multiplexing at the transmitter side is the high peak-to-average power ratio (PAPR) of the signal. Conventional solutions for this problem are to use a linear amplifier ( or to back-off the operating ...
Ismail Sh. Baqir
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

How can economic schemes curtail the increasing sex ratio at birth in China? [PDF]

open access: yes
Fertility decline, driven by the one-child policy, and son preference have contributed to an alarming difference in the number of live male and female births in China.
Shripad Tuljapurkar   +4 more
core  

Golden ratio: A subtle regulator in our body and cardiovascular system?

open access: yes, 2016
Golden ratio, which is an irrational number and also named as the Greek letter Phi (phi), is defined as the ratio between two lines of unequal length, where the ratio of the lengths of the shorter to the longer is the same as the ratio between the ...
Yetkin, Ertan   +2 more
core   +1 more source

Experimental study on the energy dissipation ratio of step-pool system

open access: yes工程科学与技术, 2013
:Step-pool system widely occurs in high gradient mountain rivers. Step-pool system dissipates flow energy efficiently, thus creates high resistance and stabilizes the stream bed.
liwenzhe
doaj  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Intelligent genetic algorithms for next-generation broadband multi-carrier CDMA wireless networks

open access: yes, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This dissertation proposes a novel intelligent system architecture for next-generation broadband multi-carrier CDMA wireless networks.
Zhang, Yang
core  

Two novel nonlinear companding schemes with iterative receiver to reduce PAPR in multi-carrier modulation systems

open access: yes, 2006
Companding transform is an efficient and simple method to reduce the Peak-to-Average Power Ratio (PAPR) for Multi-Carrier Modulation (MCM) systems.
Guo, P, Yao, W, Qu, D, Song, Y, Jiang, T
core   +1 more source

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